Glycosidases are ubiquitous enzymes that catalyze the hydrolysis of glycosidic linkages in
oligosaccharides and glycoconjugates. These enzymes play a vital role in a wide variety of …

The endoplasmic reticulum (ER) is responsible for structural transformation or folding of de
novo proteins for transport to the Golgi. When the folding capacity of the ER is exceeded or …

The use of noncovalent interactions (NCIs) has received significant attention as a pivotal
synthetic handle. Recently, the exploitation of unconventional NCIs has gained considerable …

Due to the limitations of the conventional water sample pretreatment methods, some of the
colloidal uranium (U) has long been misidentified as" dissolved" phase. In this work, the U …

The “carbohydrate chemical mimicry” exhibited by sp2‐iminosugars has been utilized to
develop practical syntheses for analogs of the branched high‐mannose‐type …

Invariant natural killer T (iNKT) cells are a subset of innate T cells displaying powerful
immunomodulatory functions. Despite extensive preclinical research on the use of iNKT …

Despite extensive research, the links between the accumulation of glycosaminoglycans
(GAGs) and the clinical features seen in patients suffering from various forms of …

Abstract Glycoside hydrolase family 20 (GH20) β-N-acetyl-d-hexosaminidase (Hex)
catalyzes the cleavage of glycosidic linkages in glycans, glycolipids and glycoproteins, and …

The conventional approach to develo** light-sensitive glycosidase activity regulators,
involving the combination of a glycomimetic moiety and a photoactive azobenzene module …

Nacional de Saúde Dr. Ricardo Jorge, me integraram como se já ali pertencesse há muito.
Por toda a convivência e diálogo diários (por vezes difícil, eu sei), pela disponibilidade de …