Salt Handling and Blood Pressure Salt intake is associated with blood pressure, but the
relationship is complex. This review highlights the interplay among renal salt transport, salt …

Intake of salt is a biological imperative, inextricably woven into physiological systems,
human societies and global culture. However, excessive salt intake is associated with high …

Rationale: High-salt diet is one of the most important risk factors for hypertension. Intestinal
flora has been reported to be associated with high salt–induced hypertension (hSIH) …

Bruce McEwen's discovery of receptors for corticosterone in the rat hippocampus introduced
higher brain circuits in the neuroendocrinology of stress. Subsequently, these receptors …

In this 30th anniversary issue review, we focus on the glucocorticoid modulation of limbic‐
prefrontocortical circuitry during stress‐co**. This action of the stress hormone is mediated …

In 1968, Bruce McEwen discovered that 3 H-corticosterone administered to
adrenalectomised rats is retained in neurons of hippocampus rather than those of …

beta‐hydroxysteroid dehydrogenases (11β‐HSDs) catalyse the conversion of active 11‐
hydroxy glucocorticoids (cortisol, corticosterone) and their inert 11‐keto forms (cortisone, 11 …

Chronic Heart Failure (CHF) is the end result of nearly all cardiovascular disease and is the
leading cause of deaths worldwide. Studies have demonstrated that intestinal flora has a …

Sodium is an essential nutrient for the human body. It is widely used as sodium chloride
(table salt) in (processed) foods and overconsumed by both children and adults, placing …

Apparent mineralocorticoid excess is an autosomal recessive form of monogenic disease
characterized by juvenile resistant low-renin hypertension, marked hypokalemic alkalosis …