1, 3, 4‐oxadiazole and its derivatives: A review on recent progress in anticancer activities
A Vaidya, D Pathak, K Shah - Chemical biology & drug design, 2021 - Wiley Online Library
Abstract The 1, 3, 4‐oxadiazole nucleus is a biologically imperative scaffold possesses
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …
Therapeutic potential of oxadiazole or furadiazole containing compounds
As we know that, Oxadiazole or furadi azole ring containing derivatives are an important
class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two …
class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two …
Novel hybrids of benzothiazole-1, 3, 4-oxadiazole-4-thiazolidinone: Synthesis, in silico ADME study, molecular docking and in vivo anti-diabetic assessment
A series of new benzothiazole-1, 3, 4-oxadiazole-4-thiazolidinone hybrid analogs (Tz1-
Tz28) were synthesized in search of potential anti-diabetic agents. Molecular docking study …
Tz28) were synthesized in search of potential anti-diabetic agents. Molecular docking study …
Synthesis of some new 1, 3, 4-oxadiazole derivatives and evaluation of their anticancer activity
In this work, some new 2-[(5-((2-acetamidophenoxy) methyl)-1, 3, 4-oxadiazol-2-yl) thio]
acetamide derivatives (4a-4l) were synthesized and studied for their anticancer activity …
acetamide derivatives (4a-4l) were synthesized and studied for their anticancer activity …
Synthesis, molecular modelling studies and ADME prediction of benzothiazole clubbed oxadiazole-Mannich bases, and evaluation of their anti-diabetic activity …
A small library of new benzothiazole clubbed oxadiazole-Mannich bases (M-1 to M-22) were
synthesized and characterized by IR, NMR, Mass and Elemental analysis results. Molecular …
synthesized and characterized by IR, NMR, Mass and Elemental analysis results. Molecular …
[PDF][PDF] Synthesis and Biological Evaluationof Novel 1, 3, 4-Oxadiazole Derivatives as Antimicrobial Agents
PB Parekar, SD Sonwane, VN Dhakane… - Journal of …, 2023 - jcdronline.org
The major drawback of current treatment of infectious diseases are challenging due to
resistance to antimicrobial agents and their side effects. In order to overcome this situation, it …
resistance to antimicrobial agents and their side effects. In order to overcome this situation, it …
1, 3, 4-Oxadiazole containing compounds as therapeutic targets for cancer therapy
MJ Ahsan - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Background: Cancer is the first or second leading cause of premature death in 134 of 183
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …
Synthesis, thymidine phosphorylase inhibitory and computational study of novel 1, 3, 4-oxadiazole-2-thione derivatives as potential anticancer agents
S Bajaj, PP Roy, J Singh - Computational Biology and Chemistry, 2018 - Elsevier
Abstract A series of novel 1, 3, 4-oxadiazole-2-thione derivatives were designed,
synthesized and evaluated for in vitro anticancer activity against breast cancer (MCF-7) cell …
synthesized and evaluated for in vitro anticancer activity against breast cancer (MCF-7) cell …
Novel 1, 3, 4-oxadiazole targets STAT3 signaling to induce antitumor effect in lung cancer
Lung cancer is the leading type of malignancy in terms of occurrence and mortality in the
global context. STAT3 is an oncogenic transcription factor that is persistently activated in …
global context. STAT3 is an oncogenic transcription factor that is persistently activated in …
Identification of phenylcarbamoylazinane-1, 3, 4-oxadiazole amides as lipoxygenase inhibitors with expression analysis and in silico studies
In search for new anti-inflammatory agents that inhibit the enzymes of arachidonic acid
pathway as the drug targets, the present article describes the screening of 1, 3, 4-oxadiazole …
pathway as the drug targets, the present article describes the screening of 1, 3, 4-oxadiazole …