The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Each follicle represents the basic functional unit of the ovary. From its very initial stage of
development, the follicle consists of an oocyte surrounded by somatic cells. The oocyte …

Deep sequencing of the gut microbiomes of 1135 participants from a Dutch population-
based cohort shows relations between the microbiome and 126 exogenous and intrinsic …

Understanding the organizational logic of neural circuits requires deciphering the biological
basis of neuronal diversity and identity, but there is no consensus on how neuron types …

Though discovered over 100 years ago, the molecular foundation of sporadic Alzheimer's
disease (AD) remains elusive. To better characterize the complex nature of AD, we …

Summary Although CD8+ T-cell-mediated autoimmune β cell destruction occurs in type 1
diabetes (T1D), the target epitopes processed and presented by β cells are unknown. To …

Pediatric-onset colitis and inflammatory bowel disease (IBD) have significant effects on the
growth of infants and children, but the etiopathogenesis underlying disease subtypes …

Pathogen-associated molecular patterns (PAMPs) and endogenous “danger” signals,
known as danger-associated molecular patterns (DAMPs), released from cells alert the …

Measurement of biomarkers has revolutionized the work-up of patients with suspected
cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are …

Neurosecretory protein VGF (non-acronymic) belongs to the granin family of neuropeptides.
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …