Mosquito-borne diseases, the most well known of which is malaria, are among the leading
causes of human deaths worldwide. Vector control is a very important part of the global …

Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Complete and accurate genome assemblies form the basis of most downstream genomic
analyses and are of critical importance. Recent genome assembly projects have relied on a …

Long-read single-molecule sequencing has revolutionized de novo genome assembly and
enabled the automated reconstruction of reference-quality genomes. However, given the …

The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains
and curates a publicly available database of annotated genomic, transcript, and protein …

Among arthropod vectors, ticks transmit the most diverse human and animal pathogens,
leading to an increasing number of new challenges worldwide. Here we sequenced and …

Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

Insects are the most speciose group of animals, but the phylogenetic relationships of many
major lineages remain unresolved. We inferred the phylogeny of insects from 1478 protein …

Background Second-generation sequencing technologies are precipitating major shifts with
regards to what kinds of genomes are being sequenced and how they are annotated. While …

Current sequencing methods produce large amounts of data, but genome assemblies
constructed from these data are often fragmented and incomplete. Incomplete and error …