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Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
MA Cannarile, M Weisser, W Jacob, AM Jegg… - … for immunotherapy of …, 2017 - Springer
The tumor-permissive and immunosuppressive characteristics of tumor-associated
macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this …
macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this …
The NF1+/- Immune Microenvironment: Dueling Roles in Neurofibroma Development and Malignant Transformation
EE White, SD Rhodes - Cancers, 2024 - mdpi.com
Simple Summary In this review, we explore how interactions between tumorigenic Schwann
cells and infiltrating immune cells shape the development and malignant transformation of …
cells and infiltrating immune cells shape the development and malignant transformation of …
Identification, synthesis and evaluation of CSF1R inhibitors using fragment based drug design
PK Machiraju, P Yedla, SP Gubbala, T Bohari… - … Biology and Chemistry, 2019 - Elsevier
Colony-stimulating factor 1 receptor is a type III receptor protein tyrosine kinase belonging to
PDGFR family. CSF1R signaling is essential for differentiation, proliferation and survival of …
PDGFR family. CSF1R signaling is essential for differentiation, proliferation and survival of …
Targeting the tumor-associated macrophages for 'Normalizing'cancer
J Kzhyshkowska, E Grigoryeva, I Larionova - … Complex Diseases: Network …, 2020 - Springer
Macrophages are a major component of the leukocyte infiltrate of tumor microenvironment.
Their involvement in tumor progression was demonstrated for many cancers, including …
Their involvement in tumor progression was demonstrated for many cancers, including …
Malignant peripheral nerve sheath tumor—from genetics to multidisciplinary treatment
AM Czarnecka, P Chmiel, P Sobczuk… - Oncology in Clinical …, 2024 - journals.viamedica.pl
Malignant peripheral nerve sheath tumor (MPNST) is an aggressive soft tissue sarcoma
(STS); it originates from nervous tissue and typically develops in proximity to nerve trunks in …
(STS); it originates from nervous tissue and typically develops in proximity to nerve trunks in …
[引用][C] The Role of Macrophages in Acute Myeloid Leukaemia Progression and Sensitivity to Chemotherapy
T Keech - 2021 - espace.library.uq.edu.au
Acute Myeloid Leukaemia (AML) is a heterogeneous neoplasm that has notoriously low
survival rates. Although treatment often leads to clinical remission, the relapse rate of AML is …
survival rates. Although treatment often leads to clinical remission, the relapse rate of AML is …