Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
Lysosomes are the primary catabolic compartments of eukaryotic cells. They degrade
extracellular material that has been internalized by endocytosis and intracellular …
extracellular material that has been internalized by endocytosis and intracellular …
Endocytic recycling
After endocytosis, most membrane proteins and lipids return to the cell surface, but some
membrane components are delivered to late endosomes or the Golgi. We now understand …
membrane components are delivered to late endosomes or the Golgi. We now understand …
Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived …
Exosomes are 40–100nm extracellular vesicles that are released from a multitude of cell
types, and perform diverse cellular functions including intercellular communication, antigen …
types, and perform diverse cellular functions including intercellular communication, antigen …
Endocytosis and molecular sorting
I Mellman - Annual review of cell and developmental biology, 1996 - annualreviews.org
▪ Abstract Endocytosis in eukaryotic cells is characterized by the continuous and regulated
formation of prolific numbers of membrane vesicles at the plasma membrane. These …
formation of prolific numbers of membrane vesicles at the plasma membrane. These …
Endocytosis
S Mukherjee, RN Ghosh… - Physiological …, 1997 - journals.physiology.org
Mammalian cells take up extracellular material by a variety of different mechanisms that are
collectively termed endocytosis. Endocytic mechanisms serve many important cellular …
collectively termed endocytosis. Endocytic mechanisms serve many important cellular …
Rab11 regulates recycling through the pericentriolar recycling endosome.
Small GTPases of the rab family are crucial elements of the machinery that controls
membrane traffic. In the present study, we examined the distribution and function of rab11 …
membrane traffic. In the present study, we examined the distribution and function of rab11 …
Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11
Two endosome populations involved in recycling of membranes and receptors to the plasma
membrane have been described, the early and the recycling endosome. However, this …
membrane have been described, the early and the recycling endosome. However, this …
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.
Small GTPases of the rab family control distinct steps of intracellular transport. The function
of their GTPase activity is not completely understood. To investigate the role of the …
of their GTPase activity is not completely understood. To investigate the role of the …
The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex
The Golgi complex is a series of membrane compartments through which proteins destined
for the plasma membrane, secretory vesicles, and lysosomes move sequentially. A model is …
for the plasma membrane, secretory vesicles, and lysosomes move sequentially. A model is …
[HTML][HTML] An iron delivery pathway mediated by a lipocalin
Despite the critical need for iron in many cellular reactions, deletion of the transferrin
pathway does not block organogenesis, suggesting the presence of alternative methods to …
pathway does not block organogenesis, suggesting the presence of alternative methods to …