Aspergillus fumigatus and Aspergillosis in 2019
JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …
Fungal secondary metabolism: regulation, function and drug discovery
NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …
Neutrophil migration in infection and wound repair: going forward in reverse
Neutrophil migration and its role during inflammation has been the focus of increased
interest in the past decade. Advances in live imaging and the use of new model systems …
interest in the past decade. Advances in live imaging and the use of new model systems …
The re-emergence of natural products for drug discovery in the genomics era
Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …
use has diminished in the past two decades, in part because of technical barriers to …
Regulation and role of fungal secondary metabolites
J Macheleidt, DJ Mattern, J Fischer… - Annual review of …, 2016 - annualreviews.org
Fungi have the capability to produce a tremendous number of so-called secondary
metabolites, which possess a multitude of functions, eg, communication signals during …
metabolites, which possess a multitude of functions, eg, communication signals during …
A comparative genomics study of 23 Aspergillus species from section Flavi
I Kjærbølling, T Vesth, JC Frisvad, JL Nybo… - Nature …, 2020 - nature.com
Section Flavi encompasses both harmful and beneficial Aspergillus species, such as
Aspergillus oryzae, used in food fermentation and enzyme production, and Aspergillus …
Aspergillus oryzae, used in food fermentation and enzyme production, and Aspergillus …
Translating biosynthetic gene clusters into fungal armor and weaponry
NP Keller - Nature chemical biology, 2015 - nature.com
Filamentous fungi are renowned for the production of a diverse array of secondary
metabolites (SMs) where the genetic material required for synthesis of a SM is typically …
metabolites (SMs) where the genetic material required for synthesis of a SM is typically …
A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen
N Raffa, NP Keller - PLoS pathogens, 2019 - journals.plos.org
Aspergillus fumigatus is a ubiquitous saprophytic mold able to grow on a diversity of material
ranging from decayed organic matter in the environment to space station cupolas [1]. Yet this …
ranging from decayed organic matter in the environment to space station cupolas [1]. Yet this …
The Macrophage-Specific Promoter mfap4 Allows Live, Long-Term Analysis of Macrophage Behavior during Mycobacterial Infection in Zebrafish
Transgenic labeling of innate immune cell lineages within the larval zebrafish allows for real-
time, in vivo analyses of microbial pathogenesis within a vertebrate host. To date, labeling of …
time, in vivo analyses of microbial pathogenesis within a vertebrate host. To date, labeling of …
From axenic to mixed cultures: technological advances accelerating a paradigm shift in microbiology
C Nai, V Meyer - Trends in microbiology, 2018 - cell.com
Since the onset of microbiology in the late 19th century, scientists have been growing
microorganisms almost exclusively as pure cultures, resulting in a limited and biased view of …
microorganisms almost exclusively as pure cultures, resulting in a limited and biased view of …