Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases
Nucleoside analogues have been in clinical use for almost 50 years and have become
cornerstones of treatment for patients with cancer or viral infections. The approval of several …
cornerstones of treatment for patients with cancer or viral infections. The approval of several …
The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold
KL Seley-Radtke, MK Yates - Antiviral research, 2018 - Elsevier
This is the first of two invited articles reviewing the development of nucleoside-analogue
antiviral drugs, written for a target audience of virologists and other non-chemists, as well as …
antiviral drugs, written for a target audience of virologists and other non-chemists, as well as …
Bioorganometallic chemistry of ferrocene
DR Van Staveren, N Metzler-Nolte - Chemical reviews, 2004 - ACS Publications
In 1951, a new compound containing iron and two cyclopentadienide ligands was reported.
1, 2 Although even the first reports noted its high and unexpected stability, the correct …
1, 2 Although even the first reports noted its high and unexpected stability, the correct …
Fluorescent analogs of biomolecular building blocks: design, properties, and applications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …
has played and continues to play key roles in modern research. Indeed, unraveling the inner …
The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold
MK Yates, KL Seley-Radtke - Antiviral research, 2019 - Elsevier
This is the second of two invited articles reviewing the development of nucleoside analogue
antiviral drugs, written for a target audience of virologists and other non-chemists, as well as …
antiviral drugs, written for a target audience of virologists and other non-chemists, as well as …
Strategies in the design of antiviral drugs
E De Clercq - Nature Reviews drug discovery, 2002 - nature.com
A decade ago, just five drugs were licensed for the treatment of viral infections. Since then,
greater understanding of viral life cycles, prompted in particular by the need to combat …
greater understanding of viral life cycles, prompted in particular by the need to combat …
Advances and perspectives in the management of varicella-zoster virus infections
G Andrei, R Snoeck - Molecules, 2021 - mdpi.com
Varicella-zoster virus (VZV), a common and ubiquitous human-restricted pathogen, causes a
primary infection (varicella or chickenpox) followed by establishment of latency in sensory …
primary infection (varicella or chickenpox) followed by establishment of latency in sensory …
Antivirals and antiviral strategies
ED Clercq - Nature Reviews Microbiology, 2004 - nature.com
In recent years, the demand for new antiviral strategies has increased markedly. There are
many contributing factors to this increased demand, including the ever-increasing …
many contributing factors to this increased demand, including the ever-increasing …
Palladium-assisted routes to nucleosides
LA Agrofoglio, I Gillaizeau, Y Saito - Chemical reviews, 2003 - ACS Publications
Palladium-Assisted Routes to Nucleosides | Chemical Reviews ACS ACS Publications
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted …
C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most Trusted …
Antiviral drug discovery and development: where chemistry meets with biomedicine
E De Clercq - Antiviral research, 2005 - Elsevier
The successful development of antiviral drugs is highly dependent on a close interaction
and collaboration between the chemist and the biologist (biomedic). This is illustrated by a …
and collaboration between the chemist and the biologist (biomedic). This is illustrated by a …