Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Colloidal self-assembly refers to a solution-processed assembly of nanometer-/micrometer-
sized, well-dispersed particles into secondary structures, whose collective properties are …

Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

A grand challenge in the fields of chemistry and materials science is the ability to construct f
the plac or a giv ement of en application. each component in or materials with absolute …

We describe a simple and robust method to construct complex three-dimensional (3D)
structures by using short synthetic DNA strands that we call “DNA bricks.” In one-step …

Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

DNA is the molecule that stores and transmits genetic information in biological systems. The
field of DNA nanotechnology takes this molecule out of its biological context and uses its …

A historical perspective of the development of spherical nucleic acid (SNA) conjugates and
other three-dimensional nucleic acid nanostructures is provided. This Perspective details the …