Immunosuppressive mechanisms of regulatory B cells
D Catalán, MA Mansilla, A Ferrier, L Soto… - Frontiers in …, 2021 - frontiersin.org
Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …
Immune regulatory function of B cells
C Mauri, A Bosma - Annual review of immunology, 2012 - annualreviews.org
B cells are regarded for their capacity to produce antibody. However, recent advances in B
cell biology have capitalized on old findings and demonstrated that B cells also release a …
cell biology have capitalized on old findings and demonstrated that B cells also release a …
B cell regulation in cancer and anti-tumor immunity
A Sarvaria, JA Madrigal, A Saudemont - Cellular & molecular …, 2017 - nature.com
The balance between immune effector cells and immunosuppressive cells and how this
regulates the tumor microenvironment has been well described. A significant contribution of …
regulates the tumor microenvironment has been well described. A significant contribution of …
CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation
The relevance of regulatory B cells in the maintenance of tolerance in healthy individuals or
in patients with immune disorders remains understudied. In healthy individuals, CD19+ …
in patients with immune disorders remains understudied. In healthy individuals, CD19+ …
B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells
B cells have paradoxical roles in autoimmunity, exerting both pathogenic and protective
effects. Pathogenesis may be antibody independent, as B cell depletion therapy (BCDT) …
effects. Pathogenesis may be antibody independent, as B cell depletion therapy (BCDT) …
Pathogenesis of immune thrombocytopenia
S Audia, M Mahévas, M Samson, B Godeau… - Autoimmunity …, 2017 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the …
response, notably supported by splenic T follicular helper cells, that stimulates the …
Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy
Abstract Interleukin-10 (IL-10) is arguably the most potent anti-inflammatory cytokine. It is
produced by almost all the innate and adaptive immune cells. These cells also serve as its …
produced by almost all the innate and adaptive immune cells. These cells also serve as its …
IL-10–producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection
A Das, G Ellis, C Pallant, AR Lopes… - The Journal of …, 2012 - journals.aai.org
A regulatory subset of B cells has been found to modulate immune responses in
autoimmunity, infection, and cancer, but it has not been investigated in the setting of human …
autoimmunity, infection, and cancer, but it has not been investigated in the setting of human …
IL-10-producing regulatory B cells (B10 cells) in autoimmune disease
I Kalampokis, A Yoshizaki, TF Tedder - Arthritis research & therapy, 2013 - Springer
B cell abnormalities contribute to the development and progress of autoimmune disease.
Traditionally, the role of B cells in autoimmune disease was thought to be predominantly …
Traditionally, the role of B cells in autoimmune disease was thought to be predominantly …
Advances in human B cell phenotypic profiling
DA Kaminski, C Wei, Y Qian, AF Rosenberg… - Frontiers in …, 2012 - frontiersin.org
To advance our understanding and treatment of disease, research immunologists have
been called-upon to place more centralized emphasis on impactful human studies. Such …
been called-upon to place more centralized emphasis on impactful human studies. Such …