Over the last decades, there was increasing evidence for the presence of innate immune
memory in living organisms. In this review, we compare the innate immune memory of …

ABSTRACT A greater ethical conscience, new global rules and a modified perception of
ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo …

The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

Multicellular organisms are constantly subjected to pathogens that might be harmful.
Although insects lack an adaptive immune system, they possess highly effective anti …

The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …

The mealworm beetle, Tenebrio molitor, is currently considered as a pest when infesting
stored grains or grain products. However, mealworms are now being promoted as a …

Current antibiotics cannot eradicate uropathogenic Escherichia coli (UPEC) biofilms,
leading to recurrent urinary tract infections. Here, we show that the insect antimicrobial …

Background Phage therapy is the therapeutic use of bacteriophages to treat highly drug
resistant bacterial infections. The current surge in bacteriophage therapy is motivated mainly …

Insects have evolved diverse interactions with a variety of microbes, such as pathogenic
fungi, bacteria, and viruses. The immune responses of insect hosts, along with the dynamic …

With the emergence of antibiotic-resistant bacteria, innovative approaches are needed for
the treatment of urinary tract infections. Boosting antimicrobial peptide expression may …