How and where did life on Earth originate? To date, various environments have been
proposed as plausible sites for the origin of life. However, discussions have focused on a …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

Homochirality is a signature of life on Earth, yet its origins remain an unsolved puzzle.
Achieving homochirality is essential for a high-yielding prebiotic network capable of …

Either to sustain autotrophy, or as a prelude to heterotrophy, organic synthesis from an
environmentally available C1 feedstock molecule is crucial to the origin of life. Recent …

The chemistry of abiotic nucleotide synthesis of RNA and DNA in the context of their
prebiotic origins on early earth is a continuing challenge. How did (or how can) the …

The nature of the first genetic polymer is the subject of major debate. Although the 'RNA
world'theory suggests that RNA was the first replicable information carrier of the prebiotic era …

At some stage in the origin of life, an informational polymer must have arisen by purely
chemical means. According to one version of the 'RNA world'hypothesis,, this polymer was …

The emergence of biopolymer building blocks is a crucial step during the origins of life,,,,–.
However, all known formation pathways rely on rare pure feedstocks and demand …

INTRODUCTION Although hundreds of organic reactions have been validated under
consensus prebiotic conditions, we still have only a fragmentary understanding of how these …

Solar radiation is the principal source of energy available to Earth and has unmatched
potential for the synthesis of organic material from primordial molecular building blocks. As …