Ferrocene-containing hybrids as potential anticancer agents: Current developments, mechanisms of action and structure-activity relationships

R Wang, H Chen, W Yan, M Zheng, T Zhang… - European Journal of …, 2020 - Elsevier
Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …

Anticancer potential of ferrocene-containing derivatives: Current and future prospective

V Tomar, P Kumar, D Sharma, RK Joshi… - Journal of Molecular …, 2024 - Elsevier
Organometallic compounds have gained popularity as potent anti-cancer therapeutic
prospects in recent years. The constant threat of drug-resistant cancer and the limited …

Synthesis, structural characterization, DFT calculations, molecular docking, and molecular dynamics simulations of a novel ferrocene derivative to unravel its potential …

MM Hammoud, M Khattab, M Abdel-Motaal… - Journal of …, 2023 - Taylor & Francis
In this article, we describe a set of subsequent five-steps chemical reactions to synthesize a
ferrocene derivative named 1-(5-(diphenylphosphaneyl) cyclopenta-1, 3-dien-1-yl) ethyl) …

Computer-aided design and synthesis of molecular imprinting polymers based on doubly oriented functional multiwalled carbon nanotubes for electrochemically …

Y Zhang, W Huang, X Yin, KA Sarpong, L Zhang… - Reactive and Functional …, 2020 - Elsevier
Bisphenol A (BPA) is a type of EDCs that can affect the endocrine system and cause a
serious of diseases. In order to develop better detection methods, this study reported a novel …

Hybridization of imidazole with various heterocycles in targeting cancer: a decade's work

G Teli, PA Chawla - ChemistrySelect, 2021 - Wiley Online Library
Cancer is the world's biggest global health concern. The prevalence and mortality rates of
cancer remain high despite significant progress in cancer therapy. The search for more …

Ferrocenyl Azoles: Versatile N‐Containing Heterocycles and their Anticancer Activities

BD Sadanala, R Trivedi - The Chemical Record, 2024 - Wiley Online Library
The medicinal chemistry of ferrocene has gained its momentum after the discovery of
biological activities of ferrocifen and ferroquine. These ferrocenyl drugs have been designed …

Benzimidazole scaffold as a potent anticancer agent with different mechanisms of action (2016–2023)

FF Hagar, SH Abbas, E Atef, D Abdelhamid… - Molecular Diversity, 2024 - Springer
Benzimidazole scaffolds have potent anticancer activity due to their structure similarity to
nucleoside. In addition, benzimidazoles could function as hydrogen donors or acceptors and …

Coumarin-annulated ferrocenyl 1, 3-oxazine derivatives possessing in vitro antimalarial and antitrypanosomal potency

M Mbaba, LMK Dingle, AI Zulu, D Laming, T Swart… - Molecules, 2021 - mdpi.com
A tailored series of coumarin-based ferrocenyl 1, 3-oxazine hybrid compounds was
synthesized and investigated for potential antiparasitic activity, drawing inspiration from the …

Synthesis, electrochemistry, DNA binding and in vitro cytotoxic activity of tripodal ferrocenyl bis-naphthalimide derivatives

YR Fan, BJ Wang, DG Jia, XB Yang, Y Huang - Journal of Inorganic …, 2021 - Elsevier
A series of tripodal ferrocenyl bis-naphthalimide derivatives were synthesized and
characterized. All of the bis-naphthalimide derivatives exhibited good DNA binding ability …

[HTML][HTML] A novel heterometallic ruthenium-silver complex as potential antitumor agent: Studies on its synthesis, in vitro assays and interactions with biomolecular …

Z **ong, M Jiang, M Zhang, Y Qiu, D Zhang… - European Journal of …, 2022 - Elsevier
Certain ruthenium compounds are found to be potent growth inhibitors for cancer cells. In
the current study, a novel ruthenium-triphenylphosphine (PPh 3) cation and silver-2 …