Microtubules provide long tracks along which a broad range of organelles and vesicles are
transported by kinesin and dynein motors. Motor protein complexes also tether cargoes to …

The mechanical properties of cells are important in tissue homeostasis and enable cell
growth, division, migration and the epithelial-mesenchymal transition. Mechanical properties …

Existing high-throughput methods to identify RNA-binding proteins (RBPs) are based on
capture of polyadenylated RNAs and cannot recover proteins that interact with …

We quantitatively analyzed particle tracking data on insulin granules expressing fluorescent
fusion proteins in MIN6 cells to better understand the motions contributing to intracellular …

Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

It is now widely appreciated that normal tissue morphology and function rely upon cells'
ability to sense and generate forces appropriate to their correct tissue context. Although the …

Cells are active systems with molecular force generation that drives complex dynamics at
the supramolecular scale. We present a quantitative study of molecular motions in cells over …

Most biochemical reactions in living cells rely on diffusive search for target molecules or
regions in a heterogeneous overcrowded cytoplasmic medium. Rapid rearrangements of the …

Intracellular transport plays an essential role in maintaining the organization of polarized
cells. Motor proteins tether and move cargos along microtubules during long-range transport …

This accessible book explores the mechanisms of cellular functioning associated with
several specific enzymatic molecules called motor proteins. It presents established results …