A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …

Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …

Background Exposure to early-life adversity is known to predict DNA methylation (DNAm)
patterns that may be related to psychiatric risk. However, few studies have investigated …

In utero exposure to environmental stress in both animals and humans could result in long-
term epigenome alterations which further lead to consequences for adaptation and …

The developmental sequelae of childhood poverty are well documented. However, it is not
poverty per se, but a multitude of risk factors associated with poverty that have a deleterious …

DNA methylation (DNAm)–an epigenetic process that regulates gene expression–may
represent a mechanism for the biological embedding of early traumatic experiences …

Stress is defined as a state of threatened or perceived as threatened homeostasis. The well-
tuned coordination of the stress response system is necessary for an organism to respond to …

Personality traits like neuroticism show both continuity and change across adolescence and
adulthood, with most pronounced changes occurring in young adulthood. It has been …

Postpartum depression (PPD) is a serious mood disorder that tends to occur after the
delivery, which may bring lifelong consequences to women and their families in terms of …