The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

Patients with ulcerative colitis and Crohn's disease are at increased risk for develo**
colorectal cancer. To date, no known genetic basis has been identified to explain colorectal …

Molecular classification of colorectal cancer is evolving. As our understanding of colorectal
carcinogenesis improves, we are incorporating new knowledge into the classification …

The potential role for commensal bacteria in colorectal carcinogenesis is explored in this
review. Most colorectal cancers (CRCs) occur sporadically and arise from the gradual …

The heterogenetic and sporadic nature of colorectal cancer has led to many epidemiological
associations with causes of this disease. As our understanding of the underlying molecular …

It is clear that a number of host-cell factors facilitate virus replication and, conversely, a
number of other factors possess inherent antiviral activity. Research, particularly over the …

Based on the high volume of bacteria and viruses that the intestine is exposed to and the
importance of infectious agents in some gastrointestinal and anogenital cancers, it is not …

Polyomaviruses are DNA tumor viruses with small circular genomes encoding only six
proteins including three structural capsid proteins. Despite this simplicity, our understanding …

Tumors are renowned as intricate systems that harbor heterogeneous cancer cells with
distinctly diverse molecular signatures, sizes and genomic contents. Among those various …

Telomere dysfunction has been associated with chromosomal instability in colorectal
carcinoma, but the consequences of telomere-dependent instability for chromosome …