Global brain inflammation in stroke

K Shi, DC Tian, ZG Li, AF Ducruet, MT Lawton… - The Lancet …, 2019 - thelancet.com
Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal
cell death and the release of factors such as damage-associated molecular patterns …

Autoantibodies in neurological disease

H Prüss - Nature reviews immunology, 2021 - nature.com
The realization that autoantibodies can contribute to dysfunction of the brain has brought
about a paradigm shift in neurological diseases over the past decade, offering up important …

The role of peripheral immune cells in the CNS in steady state and disease

M Prinz, J Priller - Nature neuroscience, 2017 - nature.com
The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …

The predictive role of systemic inflammation response index (SIRI) in the prognosis of stroke patients

Y Zhang, Z **ng, K Zhou, S Jiang - Clinical interventions in aging, 2021 - Taylor & Francis
Purpose Stroke is a disease associated with high mortality. Many inflammatory indicators
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …

Stroke and dementia risk: a systematic review and meta-analysis

E Kuźma, I Lourida, SF Moore, DA Levine… - Alzheimer's & …, 2018 - Elsevier
Introduction Stroke is an established risk factor for all-cause dementia, though meta-
analyses are needed to quantify this risk. Methods We searched Medline, PsycINFO, and …

The immunopathology of B lymphocytes during stroke-induced injury and repair

MK Malone, TA Ujas, DRS Britsch, KM Cotter… - Seminars in …, 2023 - Springer
B cells, also known as B lymphocytes or lymphoid lineage cells, are a historically
understudied cell population with regard to brain-related injuries and diseases. However, an …

Autoimmunity after ischemic stroke and brain injury

E Javidi, T Magnus - Frontiers in immunology, 2019 - frontiersin.org
Ischemic Stroke is a major cause of morbidity and mortality worldwide. Sterile inflammation
occurs after both stroke subtypes and contributes to neuronal injury and damage to the …

Time-dependent dual effect of microglia in ischemic stroke

P Fan, S Wang, S Chu, N Chen - Neurochemistry international, 2023 - Elsevier
Stroke, the third leading cause of death and disability worldwide, is classified into ischemic
or hemorrhagic, in which approximately 85% of strokes are ischemic. Ischemic stroke occurs …

Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases

Q Wang, LJ Song, ZB Ding, Z Chai, JZ Yu… - Neural regeneration …, 2022 - journals.lww.com
Ras homolog (Rho)-associated kinases (ROCKs) belong to the serine-threonine kinase
family, which plays a pivotal role in regulating the damage, survival, axon guidance, and …

[HTML][HTML] Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts

JC Zbesko, TVV Nguyen, T Yang, JB Frye… - Neurobiology of …, 2018 - Elsevier
Following stroke, the damaged tissue undergoes liquefactive necrosis, a stage of infarct
resolution that lasts for months although the exact length of time is currently unknown. One …