Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies

L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Nanogels: Synthesis, properties, and recent biomedical applications

QY Duan, YX Zhu, HR Jia, SH Wang, FG Wu - Progress in Materials …, 2023 - Elsevier
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

[HTML][HTML] Alliance with EPR effect: combined strategies to improve the EPR effect in the tumor microenvironment

J Park, Y Choi, H Chang, W Um, JH Ryu, IC Kwon - Theranostics, 2019 - ncbi.nlm.nih.gov
The use of nanomedicine for cancer treatment takes advantage of its preferential
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …

Recent advances in natural polymer-based drug delivery systems

X Tong, W Pan, T Su, M Zhang, W Dong, X Qi - Reactive and Functional …, 2020 - Elsevier
Natural polymers have been extensively explored as the vehicles for encapsulation and
delivery of drugs and other bioactive molecules, which have attracted tremendous attention …

Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation

W Gu, F Meng, R Haag, Z Zhong - Journal of controlled release, 2021 - Elsevier
The development of targeted nanomedicines for cancer therapy has been an utmost focus of
research across different fields including materials science, nanotechnology, biotechnology …

Bioinspired diselenide‐bridged mesoporous silica nanoparticles for dual‐responsive protein delivery

D Shao, M Li, Z Wang, X Zheng, YH Lao… - Advanced …, 2018 - Wiley Online Library
Controlled delivery of protein therapeutics remains a challenge. Here, the inclusion of
diselenide‐bond‐containing organosilica moieties into the framework of silica to fabricate …

Polymers for cytosolic protein delivery

J Lv, Q Fan, H Wang, Y Cheng - Biomaterials, 2019 - Elsevier
Cytosolic protein delivery offers opportunities to develop protein-based therapeutics
specifically modulate intracellular processes, especially those linked to 'undruggable'targets …

A review of recent developments of metal–organic frameworks as combined biomedical platforms over the past decade

M Moharramnejad, RE Malekshah, A Ehsani… - Advances in Colloid and …, 2023 - Elsevier
Abstract Metal–organic frameworks (MOFs), also called porous coordination polymers,
represent a class of crystalline porous materials made up of organic ligands and metal …

Aptamer-templated silver nanoclusters embedded in zirconium metal–organic framework for targeted antitumor drug delivery

F Su, Q Jia, Z Li, M Wang, L He, D Peng, Y Song… - Microporous and …, 2019 - Elsevier
In this study, we reported a targeted antitumor drug delivery system (DDS) based on the
nanocomposite of zirconium metal-organic framework (Zr-MOF, UiO-66) embedded with …

Hyaluronic acid-coated nanomedicine for targeted cancer therapy

K Kim, H Choi, ES Choi, MH Park, JH Ryu - Pharmaceutics, 2019 - mdpi.com
Hyaluronic acid (HA) has been widely investigated in cancer therapy due to its excellent
characteristics. HA, which is a linear anionic polymer, has biocompatibility, biodegradability …