The endoplasmic reticulum (ER) is a large, dynamic structure that serves many roles in the
cell including calcium storage, protein synthesis and lipid metabolism. The diverse functions …

The endoplasmic reticulum (ER) has a remarkably complex structure, composed of a single
bilayer that forms the nuclear envelope, along with a network of sheets and dynamic tubules …

INTRODUCTION The endoplasmic reticulum (ER) is a continuous, membrane-bound
organelle, spanning from the nuclear envelope to the outer cell periphery, that contacts and …

Microtubules are highly dynamic structures, which consist of α-and β-tubulin heterodimers,
and are involved in cell movement, intracellular trafficking, and mitosis. In the context of …

By using a potential-dependent J-aggregate-forming delocalized lipophilic cation, 5, 5', 6, 6'-
tetrachloro-1, 1', 3, 3'-tetraethylbenzimidazolocarbocyanine+++ iodide (JC-1), we find that …

The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the
ability to regulate single synapses. However, the anatomical basis of such specific signaling …

WE have hypothesized that end-to-end chromosome fusions observed in some tumours
could play a part in genetic instability associated with tumorigenesis and that fusion may …

The endoplasmic reticulum (ER) is a large, continuous membrane-bound organelle
comprised of functionally and structurally distinct domains including the nuclear envelope …

Organelles are dynamic yet highly organized to preserve cellular homeostasis. However, the
absence of time-resolved molecular tools for simultaneous dual-signal imaging of two …