Introduction: Regenerative medicine involves research in a number of fields and disciplines
such as stem cell research, tissue engineering and biological therapy in general. As …

The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

Induced pluripotent stem cells (iPSCs) have been derived from various somatic cell
populations through ectopic expression of defined factors. It remains unclear whether iPSCs …

The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated
that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced …

Direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides a
unique opportunity to derive patient-specific stem cells with potential applications in tissue …

Human induced pluripotent stem cells (HiPSCs) appear to be highly similar to human
embryonic stem cells (HESCs). Using two genetic lineage-tracing systems, we demonstrate …

The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for
personalized cell therapies and ushered in new opportunities for regenerative medicine …

Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES)
cells, but recent reports indicate that there may be important differences between them. We …

This chapter first introduces, from a complex adaptive system point of view, how the value of
new information can be measured in terms of the degree of structural variation it potentially …

A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for
study. One solution is to derive induced pluripotent stem cells from patients and differentiate …