Recently, visible-light-mediated photoredox catalysis has been emerging as one of the
fastest growing fields in organic chemistry because of its low cost, easy availability and …

In organic synthesis, C (sp3)–H functionalization is a revolutionary method that allows direct
alteration of unactivated C–H bonds. It can obviate the need for pre-functionalization and …

A palladium-catalyzed [3+ 2] annulation of substituted aromatic amides with maleimides
providing tricyclic heterocyclic molecules in good to moderate yields through weak carbonyl …

Abstract γ‐methylene C (sp3)− H functionalization of linear free carboxylic acids remains a
significant challenge. Here in we report a Pd (II)‐catalyzed tandem γ‐arylation and γ …

Dehydrogenation chemistry has long been established as a fundamental aspect of organic
synthesis, commonly encountered in carbonyl compounds. Transition metal catalysis …

An efficient method for the synthesis of bicyclic spirodiamine molecules via β-C (sp3)–H
bond activation of aliphatic amides, followed by cyclization with maleimides, has been …

Herein, the first merged photocatalytic pathway for the C–O cross-coupled esterification of
carboxylic acids to α-oxycarbonyl-β-ketones has been demonstrated. Decarboxylation of α …

A direct palladium-catalyzed γ-lactonization of free carboxylic acids via C–O reductive
elimination as a key step is described. Notable aspects of this protocol include the use of …

Aliphatic systems are ubiquitous in numerous natural products and pharmacoactive
compounds. Selective remote C–H functionalization of such aliphatic chains is of great …

Despite recent advances in ligand-enabled C (sp3)–H functionalization of native substrates,
controlling chemoselectivity in the presence of methyl and methylene C (sp3)–H bonds …