Recent progress in the science of complex coacervation
Complex coacervation is an associative, liquid–liquid phase separation that can occur in
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …
New frontiers for the materials genome initiative
Abstract The Materials Genome Initiative (MGI) advanced a new paradigm for materials
discovery and design, namely that the pace of new materials deployment could be …
discovery and design, namely that the pace of new materials deployment could be …
Polyelectrolyte complex coacervates: Recent developments and new frontiers
AM Rumyantsev, NE Jackson… - Annual Review of …, 2021 - annualreviews.org
Polyelectrolyte complex coacervates represent a wide class of materials with applications
ranging from coatings and adhesives to pharmaceutical technologies. They also underpin …
ranging from coatings and adhesives to pharmaceutical technologies. They also underpin …
Driving force and pathway in polyelectrolyte complex coacervation
There is notable discrepancy between experiments and coarse-grained model studies
regarding the thermodynamic driving force in polyelectrolyte complex coacervation …
regarding the thermodynamic driving force in polyelectrolyte complex coacervation …
Polyelectrolyte complex coacervation across a broad range of charge densities
Polyelectrolyte complex coacervates of homologous (co) polyelectrolytes with a near-ideally
random distribution of a charged and neutral ethylene oxide comonomer were synthesized …
random distribution of a charged and neutral ethylene oxide comonomer were synthesized …
Dehydration entropy drives liquid-liquid phase separation by molecular crowding
Complex coacervation driven liquid-liquid phase separation (LLPS) of biopolymers has
been attracting attention as a novel phase in living cells. Studies of LLPS in this context are …
been attracting attention as a novel phase in living cells. Studies of LLPS in this context are …
Unlocking the electrochemical functions of biomolecular condensates
Biomolecular condensation is a key mechanism for organizing cellular processes in a
spatiotemporal manner. The phase-transition nature of this process defines a density …
spatiotemporal manner. The phase-transition nature of this process defines a density …
Biomolecular condensates regulate cellular electrochemical equilibria
Control of the electrochemical environment in living cells is typically attributed to ion
channels. Here, we show that the formation of biomolecular condensates can modulate the …
channels. Here, we show that the formation of biomolecular condensates can modulate the …
Formation of multiphase complex coacervates and partitioning of biomolecules within them
GA Mountain, CD Keating - Biomacromolecules, 2019 - ACS Publications
Biological systems employ liquid–liquid phase separation to localize macromolecules and
processes. The properties of intracellular condensates that allow for multiple, distinct liquid …
processes. The properties of intracellular condensates that allow for multiple, distinct liquid …
Liquid–liquid phase separation in artificial cells
CD Crowe, CD Keating - Interface Focus, 2018 - royalsocietypublishing.org
Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of
intracellular compartmentalization. Because the mechanisms driving phase separations are …
intracellular compartmentalization. Because the mechanisms driving phase separations are …