[HTML][HTML] Brain-inspired learning in artificial neural networks: a review

S Schmidgall, R Ziaei, J Achterberg, L Kirsch… - APL Machine …, 2024 - pubs.aip.org
Artificial neural networks (ANNs) have emerged as an essential tool in machine learning,
achieving remarkable success across diverse domains, including image and speech …

Synaptic mechanisms regulating mood state transitions in depression

PK Parekh, SB Johnson, C Liston - Annual review of …, 2022 - annualreviews.org
Depression is an episodic form of mental illness characterized by mood state transitions with
poorly understood neurobiological mechanisms. Antidepressants reverse the effects of …

Role of Aβ in Alzheimer's-related synaptic dysfunction

H Zhang, X Jiang, L Ma, W Wei, Z Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Synaptic dysfunction is closely related to Alzheimer's disease (AD) which is also recognized
as synaptic disorder. β-amyloid (Aβ) is one of the main pathogenic factors in AD, which …

The microbiota regulate neuronal function and fear extinction learning

C Chu, MH Murdock, D **g, TH Won, H Chung… - Nature, 2019 - nature.com
Multicellular organisms have co-evolved with complex consortia of viruses, bacteria, fungi
and parasites, collectively referred to as the microbiota. In mammals, changes in the …

Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours

MT Makale, CR McDonald… - Nature Reviews …, 2017 - nature.com
Standard treatment of primary and metastatic brain tumours includes high-dose
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …

Alleviating catastrophic forgetting using context-dependent gating and synaptic stabilization

NY Masse, GD Grant, DJ Freedman - … of the National Academy of Sciences, 2018 - pnas.org
Humans and most animals can learn new tasks without forgetting old ones. However,
training artificial neural networks (ANNs) on new tasks typically causes them to forget …

Dendritic spines: Revisiting the physiological role

SB Chidambaram, AG Rathipriya, SR Bolla… - Progress in Neuro …, 2019 - Elsevier
Dendritic spines are small, thin, specialized protrusions from neuronal dendrites, primarily
localized in the excitatory synapses. Sophisticated imaging techniques revealed that …

Microglia as hunters or gatherers of brain synapses

M Pereira-Iglesias, J Maldonado-Teixido… - Nature …, 2025 - nature.com
Over a decade ago, it was discovered that microglia, the brain's immune cells, engulf
synaptic material in a process named microglial pruning. This term suggests that microglia …

Understanding the physical basis of memory: Molecular mechanisms of the engram

C Ortega-de San Luis, TJ Ryan - Journal of Biological Chemistry, 2022 - jbc.org
Memory, defined as the storage and use of learned information in the brain, is necessary to
modulate behavior and critical for animals to adapt to their environments and survive …

Structural components of synaptic plasticity and memory consolidation

CH Bailey, ER Kandel… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …