Racial and Ethnic Disparities in Peri-and Post-operative Cardiac Surgery
Abstract Purpose of Review Despite efforts to curtail its impact on medical care, race
remains a powerful risk factor for morbidity and mortality following cardiac surgery. While …
remains a powerful risk factor for morbidity and mortality following cardiac surgery. While …
Advances in cardiac pacing: arrhythmia prediction, prevention and control strategies
Cardiac arrhythmias constitute a tremendous burden on healthcare and are the leading
cause of mortality worldwide. An alarming number of people have been reported to manifest …
cause of mortality worldwide. An alarming number of people have been reported to manifest …
Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy
Abstract The heterozygous Phospholamban p. Arg14del mutation is found in patients with
dilated or arrhythmogenic cardiomyopathy. This mutation triggers cardiac contractile …
dilated or arrhythmogenic cardiomyopathy. This mutation triggers cardiac contractile …
[HTML][HTML] KairoSight-3.0: A validated optical map** software to characterize cardiac electrophysiology, excitation-contraction coupling, and alternans
Background Cardiac optical map** is an imaging technique that measures fluorescent
signals across a cardiac preparation. Dual optical imaging of voltage-sensitive and calcium …
signals across a cardiac preparation. Dual optical imaging of voltage-sensitive and calcium …
Targeted atrial fibrillation therapy and risk stratification using atrial alternans
N Muthavarapu, A Mohan, S Manga, P Sharma… - Journal of …, 2023 - mdpi.com
Atrial fibrillation (AF) is the most persistent arrhythmia today, with its prevalence increasing
exponentially with the rising age of the population. Particularly at elevated heart rates, a …
exponentially with the rising age of the population. Particularly at elevated heart rates, a …
Microvolt t-wave alternans is modulated by acute low-level tragus stimulation in patients with ischemic cardiomyopathy and heart failure
Aims: Microvolt T-wave alternans (TWA), an oscillation in T-wave morphology of the
electrocardiogram (ECG), has been associated with increased susceptibility to ventricular …
electrocardiogram (ECG), has been associated with increased susceptibility to ventricular …
[HTML][HTML] Enhanced adaptive matched filter for automated identification and measurement of electrocardiographic alternans
I Marcantoni, A Sbrollini, M Morettini… - … Signal Processing and …, 2021 - Elsevier
Electrocardiographic alternans, consisting of P-wave alternans (PWA), QRS-complex
alternans (QRSA) and T-wave alternans (TWA), is an index of cardiac risk. However, only …
alternans (QRSA) and T-wave alternans (TWA), is an index of cardiac risk. However, only …
The calcium transient coupled to the L-type calcium current attenuates cardiac alternans
Cardiac action potential (AP) alternans have been linked to the development of arrhythmia.
AP alternans may be driven by AP instabilities, Ca2+ transient (CaT) instabilities, or both …
AP alternans may be driven by AP instabilities, Ca2+ transient (CaT) instabilities, or both …
Clinical potential of beat‐to‐beat diastolic interval control in preventing cardiac arrhythmias
Life‐threatening ventricular arrhythmias and sudden cardiac death are often preceded by
cardiac alternans, a beat‐to‐beat oscillation in the T‐wave morphology or duration …
cardiac alternans, a beat‐to‐beat oscillation in the T‐wave morphology or duration …
Effects of azumolene on arrhythmia substrate in a model of recurrent long-duration ventricular fibrillation
P Chakraborty, S Massé, MA Azam, C Thollon… - Biochemical and …, 2022 - Elsevier
Background Proarrhythmic risk of conventional anti-arrhythmic agents is linked to
unintended modulation of membrane voltage dynamics. We have demonstrated that the anti …
unintended modulation of membrane voltage dynamics. We have demonstrated that the anti …