Endometriosis: where are we and where are we going?

AD Greene, SA Lang, JA Kendziorski… - Reproduction …, 2016 - pmc.ncbi.nlm.nih.gov
Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis

P Farhangnia, M Noormohammadi, AA Delbandi - Reproductive Health, 2024 - Springer
Vitamin D is a fat-soluble steroid hormone that was initially known only for regulating
calcium and phosphorus levels and maintaining bone health. However, it was later …

Unus pro omnibus, omnes pro uno: a novel, evidence-based, unifying theory for the pathogenesis of endometriosis

AS Laganà, SG Vitale, FM Salmeri, O Triolo… - Medical hypotheses, 2017 - Elsevier
The theory of retrograde menstruation as aetiopathogenesis of endometriosis formulated by
John Sampson in 1927 shows clear shortcomings: this does not explain why retrograde …

Endometrial biomarkers for the non‐invasive diagnosis of endometriosis

D Gupta, ML Hull, I Fraser, L Miller… - Cochrane Database …, 1996 - cochranelibrary.com
Background About 10% of reproductive‐aged women suffer from endometriosis, which is a
costly, chronic disease that causes pelvic pain and subfertility. Laparoscopy is the gold …

The role of the lymphatic system in endometriosis: a comprehensive review of the literature

LF Jerman, AJ Hey-Cunningham - Biology of reproduction, 2015 - academic.oup.com
Endometriosis is a benign gynecological disorder characterized by the presence of tissue
resembling the endometrium in locations outside the uterus. The pathogenesis of …

The gut microbiota: a double-edged sword in endometriosis

C Talwar, V Singh, R Kommagani - Biology of Reproduction, 2022 - academic.oup.com
Endometriosis that afflicts one in 10 women of reproductive age is characterized by growth
of endometrial tissue in the extra-uterine sites and encompasses metabolic-, immunologic …

The effects of resveratrol on the expression of VEGF, TGF-β, and MMP-9 in endometrial stromal cells of women with endometriosis

T Arablou, N Aryaeian, S Khodaverdi… - Scientific reports, 2021 - nature.com
Resveratrol is a phytochemical with anti-angiogenic, anti-inflammatory, and antioxidant
properties. The present study has evaluated the effect of resveratrol on the expression of …

Evaluation of apoptosis and angiogenesis in ectopic and eutopic stromal cells of patients with endometriosis compared to non-endometriotic controls

AA Delbandi, M Mahmoudi, A Shervin, S Heidari… - BMC women's …, 2020 - Springer
Background Endometriosis is a chronic, painful, and inflammatory disease characterized by
extra-uterine growth of endometrial tissues. Increased angiogenesis and resistance to …

Resveratrol treatment reduces expression of MCP‐1, IL‐6, IL‐8 and RANTES in endometriotic stromal cells

R Kolahdouz‐Mohammadi, F Shidfar… - Journal of Cellular …, 2021 - Wiley Online Library
Endometriosis is an inflammatory disease affecting reproductive‐aged women. Immunologic
disturbance, as well as inflammation, have crucial roles in the pathogenesis of …

Menstrual blood-derived stromal stem cells from women with and without endometriosis reveal different phenotypic and functional characteristics

S Nikoo, M Ebtekar, M Jeddi-Tehrani… - Molecular human …, 2014 - academic.oup.com
Retrograde flow of menstrual blood cells during menstruation is considered as the dominant
theory for the development of endometriosis. Moreover, current evidence suggests that …