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Cubosomes: the next generation of smart lipid nanoparticles?
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …
Non-lamellar lyotropic liquid crystalline lipid nanoparticles for the next generation of nanomedicine
Nonlamellar lyotropic liquid crystalline (LLC) lipid nanomaterials have emerged as a
promising class of advanced materials for the next generation of nanomedicine, comprising …
promising class of advanced materials for the next generation of nanomedicine, comprising …
Real‐Time pH‐Dependent Self‐Assembly of Ionisable Lipids from COVID‐19 Vaccines and In Situ Nucleic Acid Complexation
Ionisable amino‐lipid is a key component in lipid nanoparticles (LNPs), which plays a crucial
role in the encapsulation of RNA molecules, allowing efficient cellular uptake and then …
role in the encapsulation of RNA molecules, allowing efficient cellular uptake and then …
Inverse cubic and hexagonal mesophase evolution within ionizable lipid nanoparticles correlates with mRNA transfection in macrophages
mRNA lipid nanoparticle (LNP) technology presents enormous opportunities to prevent and
treat various diseases. Here, we developed a novel series of LNPs containing ionizable …
treat various diseases. Here, we developed a novel series of LNPs containing ionizable …
Paclitaxel-loaded self-assembled lipid nanoparticles as targeted drug delivery systems for the treatment of aggressive ovarian cancer
J Zhai, RB Luwor, N Ahmed, R Escalona… - … applied materials & …, 2018 - ACS Publications
Chemotherapy using cytotoxic agents, such as paclitaxel (PTX), is one of the most effective
treatments for advanced ovarian cancer. However, due to nonspecific targeting of the drug …
treatments for advanced ovarian cancer. However, due to nonspecific targeting of the drug …
Curcumin- and Fish Oil-Loaded Spongosome and Cubosome Nanoparticles with Neuroprotective Potential against H2O2-Induced Oxidative Stress in Differentiated …
Many phytochemical antioxidant compounds, including curcumin (CU), are water-insoluble
and thus require delivery carriers in order to increase their bioavailability for in vivo …
and thus require delivery carriers in order to increase their bioavailability for in vivo …
Self‐assembled nanostructured lipid systems: is there a link between structure and cytotoxicity?
Self‐assembly of lipid‐based liquid crystalline (LLC) nanoparticles is a formulation art
arising from the hydrophilic–lipophilic qualities and the geometric packing of amphiphilic …
arising from the hydrophilic–lipophilic qualities and the geometric packing of amphiphilic …
pH‐Dependent Lyotropic Liquid Crystalline Mesophase and Ionization Behavior of Phytantriol‐Based Ionizable Lipid Nanoparticles
Self‐assembled lipid nanoparticles (LNPs), serving as essential nanocarriers in recent
COVID‐19 mRNA vaccines, provide a stable and versatile platform for delivering a wide …
COVID‐19 mRNA vaccines, provide a stable and versatile platform for delivering a wide …
Effect of cholesterol on biomimetic membrane curvature and coronavirus fusion peptide encapsulation
I Milogrodzka, DT Nguyen Pham, GR Sama… - ACS …, 2023 - ACS Publications
Biomimetic cubic phases can be used for protein encapsulation in a variety of applications
such as biosensors and drug delivery. Cubic phases with a high concentration of cholesterol …
such as biosensors and drug delivery. Cubic phases with a high concentration of cholesterol …
Characterization of lipid-based lyotropic liquid crystal and effects of guest molecules on its microstructure: a systematic review
X Wang, Y Zhang, S Gui, J Huang, J Cao, Z Li, Q Li… - AAPS …, 2018 - Springer
Liquid crystals (LCs) are conventionally divided into thermotropic or lyotropic, based on the
organization and sequence of the controlled molecular system. Lipid-based lyotropic liquid …
organization and sequence of the controlled molecular system. Lipid-based lyotropic liquid …