Nuclear receptors are ligand-activated transcription factors and include the receptors for
steroid hormones, lipophilic vitamins, sterols, and bile acids. These receptors serve as …

Enzymatic stereoselectivity has typically been unrivalled by most chemical catalysts,
especially in the conversion of small substrates. According to the 'lock-and-key theory' …

Multiple lines of evidence indicate that Wnt/β-catenin signaling plays a fundamental role in
colorectal cancer (CRC) initiation and progression. Recent genome-wide data have …

Catalyst‐and chemical oxidant‐free electrochemical azole C− H aminations were
accomplished via cross‐dehydrogenative C− H/N− H functionalization. The catalyst‐free …

A general methodology for the synthesis of enantioenriched tertiary allylic aryl ethers
through Pd-catalyzed decarboxylative reactions of vinyl cyclic carbonates and phenols is …

Herein, we disclose a practical and simple procedure to synthesize 2-aminobenzoxaoles.
Simple anilines and formamides were used as substrates. The C–H bond ortho to the amino …

The oxidative intermolecular nitrogenation of C (sp3)–H bonds represents one of the most
straightforward strategies to construct nitrogen-containing molecules. However, a sacrificial …

Direct functionalization of the C (O)–N amide bond is one of the most high-profile research
directions in the last few decades; however oxidative couplings involving amide bonds and …

Vascular endothelial growth factor (VEGF) and its receptor play an important role both in
physiologic and pathologic angiogenesis, which is identified in ovarian cancer progression …

This report details a palladium-catalyzed process to access highly functionalized, optically
active allylic aryl ethers. A number of electron-deficient alkenyl triflates underwent …