Aging and wound healing of the skin: a review of clinical and pathophysiological hallmarks
Aging is a universal process that can cause diminished function of organs and various
diseases. The most striking consequences of aging can be seen visibly on the skin, which …
diseases. The most striking consequences of aging can be seen visibly on the skin, which …
[HTML][HTML] Beginning at the ends: telomeres and human disease
SA Savage - F1000Research, 2018 - ncbi.nlm.nih.gov
Studies of rare and common illnesses have led to remarkable progress in the understanding
of the role of telomeres (nucleoprotein complexes at chromosome ends essential for …
of the role of telomeres (nucleoprotein complexes at chromosome ends essential for …
Vascular senescence in cardiovascular and metabolic diseases
G Katsuumi, I Shimizu, Y Yoshida… - Frontiers in …, 2018 - frontiersin.org
In mammals, aging is associated with accumulation of senescent cells. Stresses such as
telomere shortening and reactive oxygen species induce “cellular senescence”, which is …
telomere shortening and reactive oxygen species induce “cellular senescence”, which is …
Effect of physical activity, smoking, and sleep on telomere length: a systematic review of observational and intervention studies
R Barragán, C Ortega-Azorín, JV Sorli… - Journal of clinical …, 2021 - mdpi.com
Aging is a risk factor for several pathologies, restricting one's health span, and promoting
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …
Healthy lifestyle behaviors and biological aging in the US National Health and Nutrition Examination Surveys 1999–2018
People who have a balanced diet and engage in more physical activity live longer, healthier
lives. This study aimed to test the hypothesis that these associations reflect a slowing of …
lives. This study aimed to test the hypothesis that these associations reflect a slowing of …
Physical activity and nutrition: two promising strategies for telomere maintenance?
As the world demographic structure is getting older, highlighting strategies to counteract age-
related diseases is a major public health concern. Telomeres are nucleoprotein structures …
related diseases is a major public health concern. Telomeres are nucleoprotein structures …
Correlation between telomere length and biomarkers of oxidative stress in human aging
The telomere length (TL) has increasingly been used as a biomarker of human aging
because it has been shown to predict the chances of survival and longevity. Oxidative stress …
because it has been shown to predict the chances of survival and longevity. Oxidative stress …
Role of the mtDNA mutations and mitophagy in inflammaging
SA Dabravolski, NG Nikiforov, AD Zhuravlev… - International Journal of …, 2022 - mdpi.com
Ageing is an unavoidable multi-factorial process, characterised by a gradual decrease in
physiological functionality and increasing vulnerability of the organism to environmental …
physiological functionality and increasing vulnerability of the organism to environmental …
Unravelling the role of telomere shortening with ageing and their potential association with diabetes, cancer, and related lifestyle factors
Telomeres are often considered as the 'ageing clock'that determines the lifespan at the
cellular level, forming the ends of a chromosome, which shorten each time the cell divides …
cellular level, forming the ends of a chromosome, which shorten each time the cell divides …
[HTML][HTML] Epigenetic dysregulation in cardiovascular aging and disease
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity for all sexes,
racial and ethnic groups. Age, and its associated physiological and pathological …
racial and ethnic groups. Age, and its associated physiological and pathological …