Aging and wound healing of the skin: a review of clinical and pathophysiological hallmarks

KA Khalid, AFM Nawi, N Zulkifli, MA Barkat, H Hadi - Life, 2022 - mdpi.com
Aging is a universal process that can cause diminished function of organs and various
diseases. The most striking consequences of aging can be seen visibly on the skin, which …

[HTML][HTML] Beginning at the ends: telomeres and human disease

SA Savage - F1000Research, 2018 - ncbi.nlm.nih.gov
Studies of rare and common illnesses have led to remarkable progress in the understanding
of the role of telomeres (nucleoprotein complexes at chromosome ends essential for …

Vascular senescence in cardiovascular and metabolic diseases

G Katsuumi, I Shimizu, Y Yoshida… - Frontiers in …, 2018 - frontiersin.org
In mammals, aging is associated with accumulation of senescent cells. Stresses such as
telomere shortening and reactive oxygen species induce “cellular senescence”, which is …

Effect of physical activity, smoking, and sleep on telomere length: a systematic review of observational and intervention studies

R Barragán, C Ortega-Azorín, JV Sorli… - Journal of clinical …, 2021 - mdpi.com
Aging is a risk factor for several pathologies, restricting one's health span, and promoting
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …

Healthy lifestyle behaviors and biological aging in the US National Health and Nutrition Examination Surveys 1999–2018

A Thomas, DW Belsky, Y Gu - The Journals of Gerontology …, 2023 - academic.oup.com
People who have a balanced diet and engage in more physical activity live longer, healthier
lives. This study aimed to test the hypothesis that these associations reflect a slowing of …

Physical activity and nutrition: two promising strategies for telomere maintenance?

E Balan, A Decottignies, L Deldicque - Nutrients, 2018 - mdpi.com
As the world demographic structure is getting older, highlighting strategies to counteract age-
related diseases is a major public health concern. Telomeres are nucleoprotein structures …

Correlation between telomere length and biomarkers of oxidative stress in human aging

S Yadav, PK Maurya - Rejuvenation research, 2022 - liebertpub.com
The telomere length (TL) has increasingly been used as a biomarker of human aging
because it has been shown to predict the chances of survival and longevity. Oxidative stress …

Role of the mtDNA mutations and mitophagy in inflammaging

SA Dabravolski, NG Nikiforov, AD Zhuravlev… - International Journal of …, 2022 - mdpi.com
Ageing is an unavoidable multi-factorial process, characterised by a gradual decrease in
physiological functionality and increasing vulnerability of the organism to environmental …

Unravelling the role of telomere shortening with ageing and their potential association with diabetes, cancer, and related lifestyle factors

AK Verma, P Singh, FA Al-Saeed, AE Ahmed, S Kumar… - Tissue and Cell, 2022 - Elsevier
Telomeres are often considered as the 'ageing clock'that determines the lifespan at the
cellular level, forming the ends of a chromosome, which shorten each time the cell divides …

[HTML][HTML] Epigenetic dysregulation in cardiovascular aging and disease

AB Herman, JR Occean, P Sen - The journal of cardiovascular …, 2021 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity for all sexes,
racial and ethnic groups. Age, and its associated physiological and pathological …