Osteoblast differentiation is a multistep series of events modulated by an integrated cascade
of gene expression that initially supports proliferation and the sequential expression of …

Polynuceosomes are constrained into loops or domains and are insulated from the effects of
chromatin structure and torsional strain from flanking domains by the cross-complexation of …

Eukaryotic chromatin is organized into topologically constrained loops that are attached to
the nuclear matrix. The regions of DNA that interact with the matrix are called matrix …

The role of simian virus 40 (SV40) large tumor antigen (T antigen) as a DNA helicase at the
replication fork was studied. We found that a T-antigen hexamer complex acts during the …

The organization of DNA within the nucleus has been demonstrated to be both cell and
tissue specific and is arranged in a non‐random fashion in both sperm and somatic cells …

Using a low-salt extraction procedure, we isolated nuclear scaffolds from tobacco that bind
specific plant DNA fragments in vitro. One of these fragments was characterized in more …

In this chapter the specificity of chromosomal DNA partitioning into topological loops is
discussed. Different experimental approaches used for the analysis of the above problem …

Primer recognition proteins (PRP) enable DNA polymerase alpha to utilize efficiently DNA
substrates with low primer to template ratios. We have previously identified the protein …

The specificity of eukaryotic DNA organization into loops fixed to the nuclear
matrix/chromosomal scaffold has been studied for more than fifteen years. The results and …

We have mapped the position of the alpha-globin gene cluster in the 20-to 300-kilobase
fragments of chromosomal DNA isolated from growing chicken HD3 erythroblastoid cells …