Amyloids are a broad class of proteins and peptides that can misfold and assemble into long
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …

Alzheimer's disease (AD) is a neurodegenerative disease causing progressive cognitive
decline until eventual death. AD affects millions of individuals worldwide in the absence of …

Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

Local recurrence is a common cause of treatment failure for patients with solid tumors.
Tumor-specific intraoperative fluorescence imaging may improve staging and debulking …

Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features
of Alzheimer's disease (AD). In addition to astrocyte and microglial reactivity, emerging …

Amyloid-β (Aβ) oligomers are implicated in the onset of Alzheimer's disease (AD). Herein,
quinoline-derived half-curcumin-dioxaborine (Q-OB) fluorescent probe was designed for …

Fluorescence‐based imaging in the second near infrared window (NIR‐II, 1000–1700 nm) is
extensively used in both fundamental scientific research and clinical practice, owing to its …

Non-invasive methods for the in vivo detection of hallmarks of Alzheimer's disease can
facilitate the study of the progression of the disease in mouse models and may enable its …

Recent evidence suggests the commensal microbiome regulates host immunity and
influences brain function; findings that have ramifications for neurodegenerative diseases. In …

Deposits of amyloid-β (Aβ) in the brains of rodents can be analysed by invasive intravital
microscopy on a submillimetre scale, or via whole-brain images from modalities lacking the …