Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

This narrative review article summarizes the current state of knowledge regarding the
relationship between the endocannabinoid system (ECS) and aggression across multiple …

It is hard to overestimate the influence of the endocannabinoid signaling (ECS) system on
central nervous system (CNS) function. In the 40 years since cannabinoids were found to …

With the recent legalization of inhaled cannabis for medicinal and recreational use, the
elderly represents one of the newest, rapidly growing cohorts of cannabis users. To …

The midbrain periaqueductal gray (PAG) plays a central role in pain modulation via
descending pathways. Opioids and cannabinoids are thought to activate these descending …

Chronic neuropathic pain is a debilitating pain syndrome caused by damage to the nervous
system that is poorly served by current medications. Given these problems, clinical studies …

Endocannabinoids (eCBs) and the expanded endocannabinoid system (ECS)-
“endocannabinoidome”, consists of the endogenous ligands, eCBs, their canonical and non …

Cannabidiol (CBD) is a naturally occurring non-psychoactive cannabinoid found in
Cannabis sativa, commonly known as cannabis or hemp. Although currently available CBD …

The brain and peripheral nervous system provide oversight to muscle physiology and
metabolism. Muscle is the largest organ in the body and critical for glucose sensitivity …

Growing evidence indicates that cannabidiol (CBD), a substance present in the Cannabis
sativa plant, has potential therapeutic value to regulate abnormal emotional memories …