Heterocellular electrotonic coupling between cardiac myocytes and non-excitable
connective tissue cells has been a long-established and well-researched fact in vitro …

Experimental data from human cardiac myocytes at body temperature is crucial for a
quantitative understanding of clinically relevant cardiac function and development of whole …

For over 100 years cardiac electrophysiology has been measured in the clinic. The electrical
signals that can be measured span from noninvasive ECG and body surface potentials …

Mutations in the CACNA1C gene are associated with ventricular tachycardia (VT). Although
the CACNA1C mutations were well identified in patients with cardiac arrhythmias …

Bayesian methods are advantageous for biological modelling studies due to their ability to
quantify and characterize posterior variability in model parameters. When Bayesian methods …

While the virtual physiological human (VPH) project has made great advances in human
modelling, many of the tools and insights developed as part of this initiative are also …

Interoperability is the faculty of making information systems work together. In this paper we
will distinguish a number of different forms that interoperability can take and show how they …

This manuscript presents a novel, data-driven approach to reduce a detailed cellular model
of cardiac myofilament (MF) for efficient and accurate cellular simulations towards cell-to …

We would like to update the readership of the American Journal of Physiology-Heart 23 and
Circulatory Physiology on the progress we have made in instituting the plan we laid out two …

We would like to update the readership of the American Journal of Physiology-Heart 23 and
Circulatory Physiology on the progress we have made in instituting the plan we laid out two …