[HTML][HTML] The chemistry of snake venom and its medicinal potential
The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …
Causes and consequences of snake venom variation
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …
species. This variability has serious consequences for the management of the world's 1.8 …
Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study
The World Health Organization call to halve global snakebite deaths by 2030 will require
substantial progress in India. We analyzed 2833 snakebite deaths from 611,483 verbal …
substantial progress in India. We analyzed 2833 snakebite deaths from 611,483 verbal …
Clinical aspects of snakebite envenoming and its treatment in low-resource settings
There is increasing recognition of the public health importance of snakebite envenoming.
Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 …
Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 …
Venomics and Peptidomics of Palearctic Vipers: A Clade-Wide Analysis of Seven Taxa of the Genera Vipera, Montivipera, Macrovipera, and Daboia across …
Snake venom variations are a crucial factor to understand the consequences of snakebite
envenoming worldwide, and therefore it is important to know about toxin composition …
envenoming worldwide, and therefore it is important to know about toxin composition …
Varespladib in the treatment of snakebite envenoming: development history and preclinical evidence supporting advancement to clinical trials in patients bitten by …
MR Lewin, RW Carter, IA Matteo, SP Samuel, S Rao… - Toxins, 2022 - mdpi.com
The availability of effective, reliably accessible, and affordable treatments for snakebite
envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin …
envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin …
Biogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots
Background Snakebite in India results in over 58,000 fatalities and a vast number of
morbidities annually. The majority of these clinically severe envenomings are attributed to …
morbidities annually. The majority of these clinically severe envenomings are attributed to …
Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy
Background Snake venom composition is dictated by various ecological and environmental
factors, and can exhibit dramatic variation across geographically disparate populations of …
factors, and can exhibit dramatic variation across geographically disparate populations of …
Old World Vipers—a review about snake venom proteomics of Viperinae and their variations
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …
fascinated humanity and nowadays they constitute potential resources for drug …
The rise of genomics in snake venom research: recent advances and future perspectives
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …