Analysis of culture and RNA isolation methods for precision-cut liver slices from cirrhotic rats
Precision-cut liver slices (PCLS) are increasingly used as a model to investigate anti-fibrotic
therapies. However, many studies use PCLS from healthy animals treated with pro-fibrotic …
therapies. However, many studies use PCLS from healthy animals treated with pro-fibrotic …
Rapid method for paraffin embedding of precision-cut liver slices
Precision-cut liver slices (PCLS) are tissue explants extensively used as an ex vivo model
for metabolism and toxicity studies. When in vitro assays are conducted, it is imperative to …
for metabolism and toxicity studies. When in vitro assays are conducted, it is imperative to …
[HTML][HTML] The importance of preclinical models in cholangiocarcinoma
O McGreevy, M Bosakhar, T Gilbert, M Quinn… - European Journal of …, 2024 - Elsevier
Cholangiocarcinoma (CCA) is an adenocarcinoma of the hepatobiliary system with a grim
prognosis. Incidence is rising globally and surgery is currently the only curative treatment …
prognosis. Incidence is rising globally and surgery is currently the only curative treatment …