Antigen presentation by extracellular vesicles from professional antigen-presenting cells
MFS Lindenbergh, W Stoorvogel - Annual review of …, 2018 - annualreviews.org
The initiation and maintenance of adaptive immunity require multifaceted modes of
communication between different types of immune cells, including direct intercellular …
communication between different types of immune cells, including direct intercellular …
EBV miRNAs BART11 and BART17-3p promote immune escape through the enhancer-mediated transcription of PD-L1
J Wang, J Ge, Y Wang, F **ong, J Guo, X Jiang… - Nature …, 2022 - nature.com
Epstein-Barr virus (EBV) is reportedly the first identified human tumor virus, and is closely
related to the occurrence and development of nasopharyngeal carcinoma (NPC), gastric …
related to the occurrence and development of nasopharyngeal carcinoma (NPC), gastric …
Mechanisms of cellular communication through intercellular protein transfer
Introduction• Intercellular membrane transfer a widespread phenomenon‐Intercellular
protein transfers between the cells of immune system‐Intercellular protein transfer between …
protein transfers between the cells of immune system‐Intercellular protein transfer between …
T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis
N Martínez-Martín, E Fernández-Arenas, S Cemerski… - Immunity, 2011 - cell.com
The immunological synapse (IS) serves a dual role for sustained T cell receptor (TCR)
signaling and for TCR downregulation. TC21 (Rras2) is a RRas subfamily GTPase that …
signaling and for TCR downregulation. TC21 (Rras2) is a RRas subfamily GTPase that …
Distinct roles but cooperative effect of TLR3/9 agonists and PD-1 blockade in converting the immunotolerant microenvironment of irreversible electroporation-ablated …
Irreversible electroporation (IRE) is a new cancer ablation technology, but methods to
improve IRE-induced therapeutic immunity are only beginning to be investigated. We …
improve IRE-induced therapeutic immunity are only beginning to be investigated. We …
CD4+ T cell-released exosomes inhibit CD8+ cytotoxic T-lymphocyte responses and antitumor immunity
T cells secrete bioactive exosomes (EXO), but the potential immunoregulatory effect of T-cell
EXO is largely unknown. In this study, we generated activated ovalbumin (OVA)-specific …
EXO is largely unknown. In this study, we generated activated ovalbumin (OVA)-specific …
Lymphocytes and trogocytosis-mediated signaling
Trogocytosis is the intercellular transfer of membrane and membrane-associated molecules.
This underappreciated process has been described in a variety of biological settings …
This underappreciated process has been described in a variety of biological settings …
Dendritic cells recruit T cell exosomes via exosomal LFA-1 leading to inhibition of CD8+ CTL responses through downregulation of peptide/MHC class I and Fas …
Active T cells release bioactive exosomes (EXOs). However, its potential modulation in
immune responses is elusive. In this study, we in vitro generated active OVA-specific CD8+ …
immune responses is elusive. In this study, we in vitro generated active OVA-specific CD8+ …
[HTML][HTML] Nanoliposomal vaccine containing long multi-epitope peptide E75-AE36 pulsed PADRE-induced effective immune response in mice TUBO model of breast …
The main goal of peptide-based cancer vaccines is to induce the immune system and
activation of effective T cell responses against cancerous cells. Nevertheless, the potency of …
activation of effective T cell responses against cancerous cells. Nevertheless, the potency of …
Th17 and Th17-stimulated CD8+ T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity
CD4+ Th17 cells induce antitumor immunity leading to the eradication of established tumors.
However, the mechanism of antitumour immunity and CTL activation by Th17 cells and the …
However, the mechanism of antitumour immunity and CTL activation by Th17 cells and the …