Roles of tau protein in health and disease

T Guo, W Noble, DP Hanger - Acta neuropathologica, 2017 - Springer
Tau is well established as a microtubule-associated protein in neurons. However, under
pathological conditions, aberrant assembly of tau into insoluble aggregates is accompanied …

Role of tau protein in Alzheimer's disease: The prime pathological player

S Muralidar, SV Ambi, S Sekaran, D Thirumalai… - International journal of …, 2020 - Elsevier
Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …

[HTML][HTML] Glyphosate's suppression of cytochrome P450 enzymes and amino acid biosynthesis by the gut microbiome: pathways to modern diseases

A Samsel, S Seneff - Entropy, 2013 - mdpi.com
Note added by the Publisher: The editors of the journal have been alerted to concerns over
potential bias in opinions and bias in the choice of citation sources used in this article. We …

ALS: A bucket of genes, environment, metabolism and unknown ingredients

M Zufiria, FJ Gil-Bea, R Fernandez-Torron… - Progress in …, 2016 - Elsevier
The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed
since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal …

[HTML][HTML] Formaldehyde toxicity in age-related neurological dementia

Y Kou, H Zhao, D Cui, H Han, Z Tong - Ageing Research Reviews, 2022 - Elsevier
The primordial small gaseous molecules, such as: NO, CO, H 2 S and formaldehyde (FA)
are present in the brains. Whether FA as well as the other molecules participates in brain …

Systematic and state-of the science review of the role of environmental factors in Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's Disease

ME Newell, S Adhikari, RU Halden - Science of The Total Environment, 2022 - Elsevier
The etiology of sporadic amyotrophic lateral sclerosis (ALS) is still unclear. We evaluate
environmental factors suspected to be associated with ALS for their potential linkage to …

Accumulated hippocampal formaldehyde induces age-dependent memory decline

Z Tong, C Han, W Luo, X Wang, H Li, H Luo, J Zhou… - Age, 2013 - Springer
Aging is an important factor in memory decline in aged animals and humans and in
Alzheimer's disease and is associated with the impairment of hippocampal long-term …

Tau oligomers and aggregation in Alzheimer's disease

MA Meraz‐Ríos, KI Lira‐De León… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 112, 1353–1367. Abstract We are analyzing the physiological function
of Tau protein and its abnormal pathological behavior when this protein is self‐assemble …

Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells

Y Wei, L Chen, J Chen, L Ge, RQ He - BMC cell biology, 2009 - Springer
Background D-ribose in cells and human serum participates in glycation of proteins resulting
in advanced glycation end products (AGEs) that affect cell metabolism and induce cell …

Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia

Z Tong, J Zhang, W Luo, W Wang, F Li, H Li, H Luo… - Neurobiology of …, 2011 - Elsevier
It is widely known that exogenous formaldehyde exposure induces human cognitive
impairment and animal memory loss; and recent studies show that formaldehyde at …