Current trends and challenges in the downstream purification of bispecific antibodies
SW Chen, W Zhang - Antibody therapeutics, 2021 - academic.oup.com
Bispecific antibodies (bsAbs) represent a highly promising class of biotherapeutic modality.
The downstream processing of this class of antibodies is therefore of crucial importance in …
The downstream processing of this class of antibodies is therefore of crucial importance in …
Effective flow-through polishing strategies for knob-into-hole bispecific antibodies
SW Chen, KM Hoi, FB Mahfut, Y Yang… - Bioresources and …, 2022 - Springer
Bispecific antibodies (bsAbs), though possessing great therapeutic potential, are extremely
challenging to obtain at high purity within a limited number of scalable downstream …
challenging to obtain at high purity within a limited number of scalable downstream …
Bispecific antigen binding proteins
S Imhof-Jung, C Klein, JT Regula, W Schaefer… - US Patent …, 2017 - Google Patents
US9676845B2 - Bispecific antigen binding proteins - Google Patents US9676845B2 - Bispecific
antigen binding proteins - Google Patents Bispecific antigen binding proteins Download PDF …
antigen binding proteins - Google Patents Bispecific antigen binding proteins Download PDF …
Bispecific anti-VEGF/anti-ANG-2 antibodies and their use in the treatment of ocular vascular diseases
H Duerr, F Herting, C Klein, JT Regula, M Rueth… - US Patent …, 2017 - Google Patents
The present invention relates to bispecific antibody against human vascular endothelial
growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2) of human IgG1 or …
growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2) of human IgG1 or …
Bivalent, bispecific antibodies
C Klein, W Schaefer - US Patent 10,138,293, 2018 - Google Patents
US10138293B2 - Bivalent, bispecific antibodies - Google Patents US10138293B2 - Bivalent,
bispecific antibodies - Google Patents Bivalent, bispecific antibodies Download PDF Info …
bispecific antibodies - Google Patents Bivalent, bispecific antibodies Download PDF Info …
Bispecific anti-VEGF/anti-ANG-2 antibodies and their use in the treatment of ocular vascular diseases
H Duerr, F Herting, C Klein, JT Regula… - US Patent …, 2020 - Google Patents
The present invention relates to bispecific antibody against human vascular endothelial
growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2) of human IgG1 or …
growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2) of human IgG1 or …
Bispecific binding molecules binding to VEGF and ANG2
A Gschwind, RG Ott, J Boucneau, MA Buyse, E Depla - 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
45895502&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
45895502&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Dual FC antigen binding proteins
US9982036B2 - Dual FC antigen binding proteins - Google Patents US9982036B2 - Dual FC
antigen binding proteins - Google Patents Dual FC antigen binding proteins Download PDF Info …
antigen binding proteins - Google Patents Dual FC antigen binding proteins Download PDF Info …
Bispecific anti-VEGF/anti-ANG-2 antibodies
US9708396B2 - Bispecific anti-VEGF/anti-ANG-2 antibodies - Google Patents US9708396B2 -
Bispecific anti-VEGF/anti-ANG-2 antibodies - Google Patents Bispecific anti-VEGF/anti-ANG-2 …
Bispecific anti-VEGF/anti-ANG-2 antibodies - Google Patents Bispecific anti-VEGF/anti-ANG-2 …
Antibodies and conjugates thereof
DV Perlroth, WY To, H Liang - US Patent 11,066,465, 2021 - Google Patents
0 [1*] C (= C) C (= O) OC (C) OP (= O)(O) OC [N+]([2*])([3*])[4*] Chemical compound [1*] C (=
C) C (= O) OC (C) OP (= O)(O) OC [N+]([2*])([3*])[4*] 0.000 description 13ZYGBDCIJLOIRRX …
C) C (= O) OC (C) OP (= O)(O) OC [N+]([2*])([3*])[4*] 0.000 description 13ZYGBDCIJLOIRRX …