Clathrin‐coated pits and caveolae are two of the most recognizable features of the plasma
membrane of mammalian cells. While our understanding of the machinery regulating and …

The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the
result of reasonably well understood cellular and biochemical actions of the toxin secreted …

The toxR gene of Vibrio cholerae encodes a transmembrane, DNA-binding protein that
activates transcription of the cholera toxin operon and a gene (tcpA) for the major subunit of …

The transposon TnphoA was used to generate fusions between phoA, the gene for alkaline
phosphatase (PhoA), and genes encoding proteins that are secreted by Vibrio cholerae …

Expression of more than 17 virulence genes in Vibrio cholerae is under the coordinate
control of the ToxR protein. ToxR is a transmembrane protein that binds to and activates the …

The toxR gene encodes a transcriptional activator controlling cholera toxin, pllus, and outer-
membrane protein expression in V cholerae. Nucleotide sequence and mutational analysis …

Ganglioside GM1 was isolated from the small intestinal mucosa of man, pig, and beef and
amounted to 0.1, 2.0, and 43 nmol per g fresh weight, respectively. These differences in …

The relative contributions of toxin-coregulated pilus (TCP) and cell-associated mannose-
sensitive hemagglutinin (MSHA) to the colonization ability of Vibrio cholerae O1 El Tor …

The bases of the different enzyme-immunoassay techniques are described and their
applications to the identification and quantification of antigens, haptens, and antibodies in …

More recently, however, there have occurred great advances in our knowledge of the patho-
genesis of infections due to these bacterial enteropathogens. This new information has been …