A molecular imaging primer: modalities, imaging agents, and applications

ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

Optical imaging techniques for point-of-care diagnostics

H Zhu, SO Isikman, O Mudanyali, A Greenbaum… - Lab on a Chip, 2013 - pubs.rsc.org
Improving access to effective and affordable healthcare has long been a global endeavor. In
this quest, the development of cost-effective and easy-to-use medical testing equipment that …

Digital confocal microscopy through a multimode fiber

D Loterie, S Farahi, I Papadopoulos, A Goy… - Optics express, 2015 - opg.optica.org
Acquiring high-contrast optical images deep inside biological tissues is still a challenging
problem. Confocal microscopy is an important tool for biomedical imaging since it improves …

3D printed optics with nanometer scale surface roughness

N Vaidya, O Solgaard - Microsystems & nanoengineering, 2018 - nature.com
Complex optical devices including aspherical focusing mirrors, solar concentrator arrays,
and immersion lenses were 3D printed using commercial technology and experimentally …

Confocal endomicroscopy: instrumentation and medical applications

JM Jabbour, MA Saldua, JN Bixler… - Annals of biomedical …, 2012 - Springer
Advances in fiber optic technology and miniaturized optics and mechanics have propelled
confocal endomicroscopy into the clinical realm. This high resolution, non-invasive imaging …

Subcellular-resolution molecular imaging within living tissue by fiber microendoscopy

TJ Muldoon, MC Pierce, DL Nida, MD Williams… - Optics express, 2007 - opg.optica.org
Conventional histopathology involves sampling, sectioning and staining of tissue specimens
prior to microscopic evaluation, and provides diagnostic information at a single location and …

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging

ME Lobatto, C Calcagno, A Millon, ML Senders, F Fay… - ACS …, 2015 - ACS Publications
Atherosclerosis is a major cause of global morbidity and mortality that could benefit from
novel targeted therapeutics. Recent studies have shown efficient and local drug delivery …

Image computing for fibre-bundle endomicroscopy: A review

A Perperidis, K Dhaliwal, S McLaughlin… - Medical image …, 2020 - Elsevier
Endomicroscopy is an emerging imaging modality, that facilitates the acquisition of in vivo, in
situ optical biopsies, assisting diagnostic and potentially therapeutic interventions. While …

MEMS gratings and their applications

G Zhou, ZH Lim, Y Qi, FS Chau… - International Journal of …, 2021 - Taylor & Francis
Grating plays an essential role in various optical systems owing to its unique dispersion
properties. In recent years, there is increasing demand to miniaturize optical systems for a …

Trends in fluorescence image-guided surgery for gliomas

JTC Liu, D Meza, N Sanai - Neurosurgery, 2014 - journals.lww.com
Mounting evidence suggests that a more extensive surgical resection is associated with an
improved life expectancy for both low-grade and high-grade glioma patients. However …