Hydrophilic interaction liquid chromatography (HILIC)—a powerful separation technique
B Buszewski, S Noga - Analytical and bioanalytical chemistry, 2012 - Springer
Hydrophilic interaction liquid chromatography (HILIC) provides an alternative approach to
effectively separate small polar compounds on polar stationary phases. The purpose of this …
effectively separate small polar compounds on polar stationary phases. The purpose of this …
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …
MZmine 2: modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
Background Mass spectrometry (MS) coupled with online separation methods is commonly
applied for differential and quantitative profiling of biological samples in metabolomic as well …
applied for differential and quantitative profiling of biological samples in metabolomic as well …
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …
[HTML][HTML] The human urine metabolome
S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
XCMS Online: a web-based platform to process untargeted metabolomic data
Recently, interest in untargeted metabolomics has become prevalent in the general scientific
community among an increasing number of investigators. The majority of these …
community among an increasing number of investigators. The majority of these …
Global metabolic profiling procedures for urine using UPLC–MS
The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies
Abstract Partial Least Squares-Discriminant Analysis (PLS-DA) is a PLS regression method
with a special binary 'dummy'y-variable and it is commonly used for classification purposes …
with a special binary 'dummy'y-variable and it is commonly used for classification purposes …
Stationary and mobile phases in hydrophilic interaction chromatography: a review
P Jandera - Analytica chimica acta, 2011 - Elsevier
Hydrophilic interaction chromatography (HILIC) is valuable alternative to reversed-phase
liquid chromatography separations of polar, weakly acidic or basic samples. In principle, this …
liquid chromatography separations of polar, weakly acidic or basic samples. In principle, this …
Column characterization and selection systems in reversed-phase high-performance liquid chromatography
Reversed-phase high-performance liquid chromatography (RP-HPLC) is the most popular
chromatographic mode, accounting for more than 90% of all separations. HPLC itself owes …
chromatographic mode, accounting for more than 90% of all separations. HPLC itself owes …