A comprehensive review of human trophoblast fusion models: recent developments and challenges
X Li, ZH Li, YX Wang, TH Liu - Cell Death Discovery, 2023 - nature.com
As an essential component of the maternal-fetal interface, the placental syncytiotrophoblast
layer contributes to a successful pregnancy by secreting hormones necessary for …
layer contributes to a successful pregnancy by secreting hormones necessary for …
Exploring maternal-fetal interface with in vitro placental and trophoblastic models
X Liu, G Wang, H Huang, X Lv, Y Si, L Bai… - Frontiers in Cell and …, 2023 - frontiersin.org
The placenta, being a temporary organ, plays a crucial role in facilitating the exchange of
nutrients and gases between the mother and the fetus during pregnancy. Any abnormalities …
nutrients and gases between the mother and the fetus during pregnancy. Any abnormalities …
Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape
The extravillous trophoblast cell lineage is a key feature of placentation and successful
pregnancy. Knowledge of transcriptional regulation driving extravillous trophoblast cell …
pregnancy. Knowledge of transcriptional regulation driving extravillous trophoblast cell …
TFEB controls expression of human syncytins during cell–cell fusion
During human development, a temporary organ is formed, the placenta, which invades the
uterine wall to support nutrient, oxygen, and waste exchange between the mother and fetus …
uterine wall to support nutrient, oxygen, and waste exchange between the mother and fetus …
[HTML][HTML] Human uterine natural killer cells regulate differentiation of extravillous trophoblast early in pregnancy
In humans, balanced invasion of trophoblast cells into the uterine mucosa, the decidua, is
critical for successful pregnancy. Evidence suggests that this process is regulated by uterine …
critical for successful pregnancy. Evidence suggests that this process is regulated by uterine …
CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development
T Shimizu, A Oike, EH Kobayashi… - Proceedings of the …, 2023 - National Acad Sciences
The placenta serves as the interface between the mother and fetus, facilitating the exchange
of gases and nutrients between their separate blood circulation systems. Trophoblasts in the …
of gases and nutrients between their separate blood circulation systems. Trophoblasts in the …
Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies
BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …
associated with placental dysfunction, more investigations are devoted to improving the …
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development
JG Lee, JM Yon, G Kim, SG Lee, CY Kim… - Nature …, 2024 - nature.com
Proper placental development in early pregnancy ensures a positive outcome later on. The
developmental relationship between the placenta and embryonic organs, such as the heart …
developmental relationship between the placenta and embryonic organs, such as the heart …
Effects of Prenatal Exposure to Bisphenol A Substitutes, Bisphenol S and Bisphenol F, on Offspring's Health: Evidence from Epidemiological and Experimental Studies
Pregnancy and lactation are critical periods for human well-being and are sensitive windows
for pollutant exposure. Bisphenol A (BPA) is well demonstrated as a toxicant and has been …
for pollutant exposure. Bisphenol A (BPA) is well demonstrated as a toxicant and has been …
Epigenetic dynamics of partially methylated domains in human placenta and trophoblast stem cells
H Toh, H Okae, K Shirane, T Sato, H Hamada… - BMC genomics, 2024 - Springer
Background The placenta is essential for nutrient exchange and hormone production
between the mother and the develo** fetus and serves as an invaluable model for …
between the mother and the develo** fetus and serves as an invaluable model for …