In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …

Melanocortin receptors have emerged as important targets with a very unusual versatility, as
their widespread distribution on multiple tissues (eg skin, adrenal glands, brain, immune …

This review considers three aspects of recent work on the role of KNDy neurons in GnRH
pulse generation in ruminants. First, work on basic mechanisms of pulse generation …

Obesity has emerged as a critical and urgent health burden during the current global
pandemic. Among multiple genetic causes, melanocortin receptor‐4 (MC4R), involved in …

The central melanocortin system links nutrition to energy expenditure, with melanocortin-4
receptor (MC4R) controlling appetite and food intake, and MC3R regulating timing of sexual …

Purpose The melanocortin system has been implicated in regulating various physiological
pathways including skin and hair pigmentation, energy homeostasis, food intake …

The neural melanocortin receptors (MCRs), melanocortin-3 and-4 receptors (MC3R and
MC4R), play essential non-redundant roles in the regulation of energy homeostasis …