Beta 2-microglobulin regulates amyloid precursor-like protein 2 expression and the migration of pancreatic cancer cells

BH Sliker, BT Goetz, HL Peters, BJ Poelaert… - Cancer Biology & …, 2019 - Taylor & Francis
ABSTRACT Beta 2-microglobulin (β2m) is a component of the major histocompatibility
complex (MHC) class I molecule, which presents tumor antigens to T lymphocytes to trigger …

Clinicopathological correlations of mesenteric fibrosis and evaluation of a novel biomarker for fibrosis detection in small bowel neuroendocrine neoplasms

FM Laskaratos, D Mandair, A Hall, S Alexander… - Endocrine, 2020 - Springer
Purpose Mesenteric fibrosis (MF) in small intestinal neuroendocrine neoplasms (SINENs) is
often associated with significant morbidity and mortality. The detection of MF is usually …

Novel role of APP cleavage by ADAM10 for breast cancer metastasis

J Wozniak, A Ludwig - EBioMedicine, 2018 - thelancet.com
Cleavage of the amyloid precursor protein (APP) at the membraneproximal extracellular
position, termed the alpha secretase site, prevents the generation of amyloidogenic Aβ …

Advances in research on the innate immune system of Drosophila melanogaster.

HU Qi-Hao, LU Yu-Zhen… - Chinese Journal of …, 2019 - search.ebscohost.com
The innate immune system plays a critical role in the ability of insects to adapt to changing
environments, and its underlying mechanism has become a new area of research in pest …

Clinical outcomes and mechanisms of mesenteric fibrosis in small bowel neuroendocrine tumours

FM Laskaratos - 2020 - discovery.ucl.ac.uk
Small intestinal neuroendocrine tumours (SI NETs) are relatively rare, indolent tumours
arising from the enterochromaffin cells of the small bowel. They can be associated with the …