Stem cell-based cell carrier for targeted oncolytic virotherapy: translational opportunity and open questions
Oncolytic virotherapy for cancer is an innovative therapeutic option where the ability of a
virus to promote cell lysis is harnessed and reprogrammed to selectively destroy cancer …
virus to promote cell lysis is harnessed and reprogrammed to selectively destroy cancer …
Recent progress in the research of suicide gene therapy for malignant glioma
Malignant glioma, which is characterized by diffuse infiltration into the normal brain
parenchyma, is the most aggressive primary brain tumor with dismal prognosis. Over the …
parenchyma, is the most aggressive primary brain tumor with dismal prognosis. Over the …
CD73 promotes glioblastoma pathogenesis and enhances its chemoresistance via A2B adenosine receptor signaling
A Yan, ML Joachims, LF Thompson… - Journal of …, 2019 - Soc Neuroscience
Glioblastoma (GB) is one of the deadliest brain cancers to afflict humans, and it has a very
poor survival rate even with treatment. The extracellular adenosine-generating enzyme …
poor survival rate even with treatment. The extracellular adenosine-generating enzyme …
Comparative analysis of differentially secreted proteins in serum-free and serum-containing media by using BONCAT and pulsed SILAC
Despite the increased interest in secretomes associated with paracrine/autocrine
mechanisms, the majority of mass spectrometric cell secretome studies have been …
mechanisms, the majority of mass spectrometric cell secretome studies have been …
Hyperbaric oxygen promotes neural stem cell proliferation by activating vascular endothelial growth factor/extracellular signal-regulated kinase signaling after …
Y Yang, H Wei, X Zhou, F Zhang, C Wang - Neuroreport, 2017 - journals.lww.com
Abstract Hyperbaric oxygen (HBO) therapy and neural stem cell (NSC) transplantation can
improve traumatic brain injury (TBI) clinically. This study aimed to investigate the mechanism …
improve traumatic brain injury (TBI) clinically. This study aimed to investigate the mechanism …
Zika virus causes persistent infection in porcine conceptuses and may impair health in offspring
J Darbellay, B Cox, K Lai, M Delgado-Ortega… - …, 2017 - thelancet.com
Outcomes of Zika virus (ZIKV) infection in pregnant women vary from the birth of
asymptomatic offspring to abnormal development and severe brain lesions in fetuses and …
asymptomatic offspring to abnormal development and severe brain lesions in fetuses and …
Engineered cells as glioblastoma therapeutics
A Ramanathan, IAJ Lorimer - Cancer Gene Therapy, 2022 - nature.com
In spite of significant recent advances in our understanding of the genetics and cell biology
of glioblastoma, to date, this has not led to improved treatments for this cancer. In addition to …
of glioblastoma, to date, this has not led to improved treatments for this cancer. In addition to …
Network analysis and the impact of Aflibercept on specific mediators of angiogenesis in HUVEC cells
Angiogenesis, inflammation and endothelial cells' migration and proliferation exert
fundamental roles in different diseases. However, more studies are needed to identify key …
fundamental roles in different diseases. However, more studies are needed to identify key …
Mesenchymal stem cells mediated drug delivery in tumor-targeted therapy
M **e, L Tao, Z Zhang, W Wang - Current Drug Delivery, 2021 - ingentaconnect.com
Mesenchymal Stem Cells (MSCs) possess unique properties that make them potential
carriers for cancer therapy. MSCs have been documented to have low immunogenicity …
carriers for cancer therapy. MSCs have been documented to have low immunogenicity …
[PDF][PDF] Curcumin Inhibits Bladder Cancer by Inhibiting Invasion via AKT/MMP14 Pathway
K Wang, W **ao, Q Zeng - Discovery Medicine, 2024 - scholar.archive.org
Background: Bladder cancer is a malignant tumor of the urinary and reproductive tract that
seriously threatens human health. It is urgent to develop new drugs for bladder cancer. This …
seriously threatens human health. It is urgent to develop new drugs for bladder cancer. This …