Unhealthy vascular aging promotes atherogenesis, which may lead to significant internal
carotid artery stenosis (CAS) in 5 to 7.5% of older adults. The pathogenic factors that …

In this work, we introduce an algorithmic approach to generate microvascular networks
starting from larger vessels that can be reconstructed without noticeable segmentation …

The cerebral circulation is unique in its ability to maintain blood flow to the brain under
widely varying physiologic conditions. Incorporating this autoregulatory response is …

Carotid artery stenosis (CAS) often requires surgical intervention through carotid
endarterectomy (CEA) to prevent stroke. Accurate cerebrovascular risk assessments are …

Carotid artery stenosis (CAS) affects approximately 5–7.5% of older adults and is
recognized as a significant risk factor for vascular cognitive impairment (VCI). The impact of …

In this work, we consider 2 kinds of model reduction techniques to simulate blood flow
through the largest systemic arteries, where a stenosis is located in a peripheral artery, ie, in …

The goal of this work is to assess the impact of vascular anatomy definition degree in the
predictions of blood flow models of the arterial network. To this end, results obtained with an …

The goal of this paper is to develop a numerical model for physiological mechanisms that
help to compensate reduced blood flow caused by a peripheral arterial stenosis. Thereby …

This thesis is concerned with the simulation of blood flow and mass transport in vascularized
human tissue. Our mathematical model is based on a domain decomposition approach, ie …

In this chapter, we will discuss the utility of transcranial Doppler to assess cerebral
hemodynamics and how to apply it to understand the cerebral blood flow changes in acute …