Nanomaterial-based CT contrast agents and their applications in image-guided therapy

Z Jiang, M Zhang, P Li, Y Wang, Q Fu - Theranostics, 2023 - pmc.ncbi.nlm.nih.gov
Computed tomography (CT), a diagnostic tool with clinical application, comprehensive
coverage, and low cost, is used in hospitals worldwide. However, CT imaging fails to …

Cu single atom nanozyme based high‐efficiency mild photothermal therapy through cellular metabolic regulation

M Chang, Z Hou, M Wang, D Wen, C Li… - Angewandte …, 2022 - Wiley Online Library
Upregulation of heat shock proteins (HSPs) drastically compromises the treatment effect of
mild photothermal therapy (PTT). Herein, we designed a polyporous Cu single atom …

Bifunctional cascading nanozymes based on carbon dots promotes photodynamic therapy by regulating hypoxia and glycolysis

T Luo, H Yang, R Wang, Y Pu, Z Cai, Y Zhao, Q Bi… - ACS …, 2023 - ACS Publications
Photodynamic therapy (PDT) still faces great challenges with suitable photosensitizers,
oxygen supply, and reactive oxygen species (ROS) accumulation, especially in the tumor …

Virus-mimicking nanosystems: from design to biomedical applications

HY Liu, X Li, ZG Wang, SL Liu - Chemical Society Reviews, 2023 - pubs.rsc.org
Nanomedicine, as an interdisciplinary discipline involving the development and application
of nanoscale materials and technologies, is rapidly develo** under the impetus of …

NIR‐activatable heterostructured nanoadjuvant CoP/NiCoP executing lactate metabolism interventions for boosted photocatalytic hydrogen therapy and …

C Yang, J Zhang, M Chang, J Tan, M Yuan… - Advanced …, 2024 - Wiley Online Library
Abstract Near‐infrared (NIR) laser‐induced photoimmunotherapy has aroused great interest
due to its intrinsic noninvasiveness and spatiotemporal precision, while immune evasion …

Modulating Nanozyme‐Based Nanomachines via Microenvironmental Feedback for Differential Photothermal Therapy of Orthotopic Gliomas

N Yin, Y Wang, Y Huang, Y Cao, L **, J Liu… - Advanced …, 2023 - Wiley Online Library
Gliomas are common and refractory primary tumors closely associated with the fine
structures of the brain. Photothermal therapy (PTT) has recently shown promise as an …

Self-stablized monodispersing nano-MOFs for controlled enzyme delivery

P Gong, H Cui, C Li, S Song, Y Gong, J Li… - Chemical Engineering …, 2024 - Elsevier
Controlled loading more than one active cargos on metal–organic frameworks (MOFs) and
kee** monodispersity have long been a great challenge due to easy agglomeration and …

A multiple-response cascade nanoreactor for starvation and deep catalysis chemodynamic assisted near-infrared-II mild photothermal therapy

Q Yu, J Zhou, H Wang, Y Liu, H Zhou… - … & Biomedical Imaging, 2023 - ACS Publications
Photothermal therapy (PTT) is hampered by the limited capacity of light penetration, non-
specific thermal diffusion damage to surrounding healthy tissues, and thermoresistance …

Dual-targeted delivery of temozolomide by multi-responsive nanoplatform via tumor microenvironment modulation for overcoming drug resistance to treat glioblastoma

X Chen, Y Zheng, Q Zhang, Q Chen, Z Chen… - Journal of …, 2024 - Springer
Glioblastoma (GBM) is the most aggressive primary brain tumor with low survival rate.
Currently, temozolomide (TMZ) is the first-line drug for GBM treatment of which efficacy is …

Fe-HCOF-PEG2000 as a Hypoxia-Tolerant Photosensitizer to Trigger Ferroptosis and Enhance ROS-Based Cancer Therapy

H Peng, Q Jiang, W Mao, Z Hu, Q Wang… - International Journal …, 2024 - Taylor & Francis
Background The hypoxic tumor microenvironment and single mechanisms severely limit the
photodynamic therapy (PDT) efficiency of covalent organic framework (COF) nanoparticles …