Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Molecular substrates for the construction of afterglow imaging probes in disease diagnosis and treatment

X Wang, K Pu - Chemical Society Reviews, 2023 - pubs.rsc.org
Afterglow, an intrinsic phenomenon of persistent luminescence emitted from chemical
defects after light irradiation, has shown tremendous promise for applications in bioimaging …

Molecular radio afterglow probes for cancer radiodynamic theranostics

J Huang, L Su, C Xu, X Ge, R Zhang, J Song, K Pu - Nature Materials, 2023 - nature.com
X-ray-induced afterglow and radiodynamic therapy tackle the tissue penetration issue of
optical imaging and phototherapy. However, inorganic nanophosphors used in this therapy …

Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

C Xu, J Huang, Y Jiang, S He, C Zhang… - Nature Biomedical …, 2023 - nature.com
Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

Rational design of NIR-II AIEgens with ultrahigh quantum yields for photo-and chemiluminescence imaging

H Shen, F Sun, X Zhu, J Zhang, X Ou… - Journal of the …, 2022 - ACS Publications
Fluorescence imaging in the second near-infrared window (NIR-II, 1000–1700 nm) using
small-molecule dyes has high potential for clinical use. However, many NIR-II dyes suffer …

Molecularly engineered room-temperature phosphorescence for biomedical application: from the visible toward second near-infrared window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

Chemiluminescent conjugated polymer nanoparticles for deep-tissue inflammation imaging and photodynamic therapy of cancer

L Li, X Zhang, Y Ren, Q Yuan, Y Wang… - Journal of the …, 2024 - ACS Publications
Deep-tissue optical imaging and photodynamic therapy (PDT) remain a big challenge for the
diagnosis and treatment of cancer. Chemiluminescence (CL) has emerged as a promising …

Enhancing Purely Organic Room Temperature Phosphorescence via Supramolecular Self‐Assembly

H Zheng, Z Zhang, S Cai, Z An, W Huang - Advanced Materials, 2024 - Wiley Online Library
Long‐lived and highly efficient room temperature phosphorescence (RTP) materials are in
high demand for practical applications in lighting and display, security signboards, and anti …

“Four-in-one” design of a hemicyanine-based modular scaffold for high-contrast activatable molecular afterglow imaging

Y Liu, L Teng, XF Lou, XB Zhang… - Journal of the American …, 2023 - ACS Publications
Afterglow luminescence (long persistent luminescence) holds great potential for
nonbackground molecular imaging. However, current afterglow probes are mainly …

In vivo ultrasound-induced luminescence molecular imaging

Y Wang, Z Yi, J Guo, S Liao, Z Li, S Xu, B Yin, Y Liu… - Nature …, 2024 - nature.com
Optical imaging is crucial to study biological or pathological processes and diagnose
diseases. However, poor tissue penetration typically limits conventional optical imaging …