Mucosal IL13RA2 expression predicts nonresponse to anti‐TNF therapy in Crohn's disease
B Verstockt, S Verstockt, B Creyns… - Alimentary …, 2019 - Wiley Online Library
Background Ileocolonic expression of IL13RA2 has been identified as a predictive marker
for nonresponsiveness to infliximab (IFX) in patients with Crohn's disease (CD). Aim To …
for nonresponsiveness to infliximab (IFX) in patients with Crohn's disease (CD). Aim To …
Genistein modulates signaling pathways and targets several epigenetic markers in HeLa cells
Background: Several epigenetic changes are responsible for transcriptional alterations of
signaling pathways and tumour suppressor genes (TSGs) contributing to carcinogenesis …
signaling pathways and tumour suppressor genes (TSGs) contributing to carcinogenesis …
Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding …
Background The human proteins TMTC1, TMTC2, TMTC3 and TMTC4 have been
experimentally shown to be components of a new O-mannosylation pathway. Their own …
experimentally shown to be components of a new O-mannosylation pathway. Their own …
Elucidating potential molecular signatures through host-microbe interactions for reactive arthritis and inflammatory bowel disease using combinatorial approach
Abstract Reactive Arthritis (ReA), a rare seronegative inflammatory arthritis, lacks exquisite
classification under rheumatic autoimmunity. ReA is solely established using differential …
classification under rheumatic autoimmunity. ReA is solely established using differential …
Inhibition of C298S mutant of human aldose reductase for antidiabetic applications: Evidence from in silico elementary mode analysis of biological network model
Human aldose reductase (hAR) is the key enzyme in sorbitol pathway of glucose utilization
and is implicated in the etiology of secondary complications of diabetes, such as …
and is implicated in the etiology of secondary complications of diabetes, such as …
[HTML][HTML] Prognostic value of TMTC1 in pan-cancer analysis
Y Zhang, D Wu, T Yu, Y Liu, C Zhao, R Xue - Heliyon, 2024 - cell.com
Background Transmembrane and tetratricopeptide repeat containing 1 (TMTC1) is a
recently discovered enzyme involved in the O-mannosylation of cadherins and …
recently discovered enzyme involved in the O-mannosylation of cadherins and …
Upregulation of TMEM45A promoted the progression of Clear Cell Renal Cell Carcinoma in vitro
H Jiang, H Chen, P Wan, M Liang… - Journal of Inflammation …, 2021 - Taylor & Francis
Background Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive
type of primary kidney cancer worldwide. Transmembrane protein 45A (TMEM45A) has …
type of primary kidney cancer worldwide. Transmembrane protein 45A (TMEM45A) has …
AS DOENÇAS INFLAMATÓRIAS INTESTINAIS E OS ACOMETIMENTOS ARTICULARES: UM PANORAMA DAS EVIDÊNCIAS CIENTÍFICAS
AWO Gonçalves… - Brazilian Journal of …, 2024 - bjihs.emnuvens.com.br
Introdução: As doenças inflamatórias intestinais (DII), incluindo a Doença de Crohn e a
Retocolite Ulcerativa, são condições que podem ter implicações além do trato digestivo …
Retocolite Ulcerativa, são condições que podem ter implicações além do trato digestivo …
Machine learning based risk assessment and early diagnostic model of inflammatory bowel disease associated arthropathy
A Verma, B Rathi, S Sharda - IOP conference series: materials …, 2021 - iopscience.iop.org
Inflammatory bowel disease (IBD) is a persistent idiopathic disorder responsible for
intestinal inflammatory conditions. IBD exhibits several extraintestinal manifestations, the …
intestinal inflammatory conditions. IBD exhibits several extraintestinal manifestations, the …
An integrated data analysis and computational approach to reveal gene signatures for paediatric Tuberculosis meningitis related to non-tuberculosis patients
AK Verma, T Singh - 2025 - researchsquare.com
The global disease burden remains greatly influenced by tuberculosis. Its most critical form,
Tuberculosis meningitis (TBM) affects both adults and children who face high rates of …
Tuberculosis meningitis (TBM) affects both adults and children who face high rates of …