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The incentive-sensitization theory of addiction 30 years on
The incentive-sensitization theory (IST) of addiction was first published in 1993, proposing
that (a) brain mesolimbic dopamine systems mediate incentive motivation (“wanting”) for …
that (a) brain mesolimbic dopamine systems mediate incentive motivation (“wanting”) for …
Pornography use, problematic pornography use, impulsivity, and sensation seeking: a meta-analysis
Background While some individuals engage in recreational pornography use (PU), others
may develop an uncontrolled pattern of use termed problematic pornography use (PPU) …
may develop an uncontrolled pattern of use termed problematic pornography use (PPU) …
The imbalance of self-reported wanting and liking is associated with the degree of attentional bias toward smoking-related stimuli in low nicotine dependence smokers
Background and aims The Incentive Sensitization Theory (IST) offers a comprehensive
framework that explains how attentional mechanisms contribute to the maintenance and …
framework that explains how attentional mechanisms contribute to the maintenance and …
Personalized repetitive transcranial magnetic stimulation guided by the spectral electroencephalogram may enhance and democratize therapy for autism spectrum …
MT Makale, K Blum, A Bowirrat, K Sunder… - Medical …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a genetically heterogeneous group of
neurodevelopmental disorders that affect 1 in 36 children (CDC data) and have …
neurodevelopmental disorders that affect 1 in 36 children (CDC data) and have …
[HTML][HTML] Genetic Addiction risk and psychological profiling analyses for “Preaddiction” Severity Index
K Blum, D Han, A Bowirrat, BW Downs… - Journal of personalized …, 2022 - mdpi.com
Since 1990, when our laboratory published the association of the DRD2 Taq A1 allele and
severe alcoholism in JAMA, there has been an explosion of genetic candidate association …
severe alcoholism in JAMA, there has been an explosion of genetic candidate association …
The imbalance of wanting and liking contributes to a bias of internal attention towards positive consequences of tobacco smoking
Previous studies have shown that addiction is associated with an attentional bias towards
external stimuli. However, it is currently unclear whether this bias extends to internal …
external stimuli. However, it is currently unclear whether this bias extends to internal …
A proof of Concept Study to assess the Imbalance of Self-reported Wanting and Liking as a predictor of problematic addictive behaviors
Tolerance, one of the key features of addiction, is a highly debated criterion for behaviors,
considered controversial and difficult to assess. The Incentive-Sensitization Theory of …
considered controversial and difficult to assess. The Incentive-Sensitization Theory of …
Wanting and liking of Facebook functions and their correlation to problematic use
D Lakatos, B Kovács, I Czigler, Z Demetrovics… - Scientific Reports, 2025 - nature.com
A key question about social media use is whether it constitutes an addiction. A possible
frame of reference to investigate this question is the Incentive Sensitizations Theory (IST), as …
frame of reference to investigate this question is the Incentive Sensitizations Theory (IST), as …
Comorbidity of problematic substance use and other addictive behaviors and anxiety, depression, and post-traumatic stress disorder: a network analysis
D Shmulewitz, MD Levitin, V Skvirsky, M Vider… - Psychological …, 2024 - cambridge.org
BackgroundAmong those with common mental health disorders (eg mood, anxiety, and
stress disorders), comorbidity of substance and other addictive disorders is prevalent. To …
stress disorders), comorbidity of substance and other addictive disorders is prevalent. To …
The role of estrogen signaling and exercise in drug abuse: A review
R Ahmed, S Zyla, N Hammond, K Blum, PK Thanos - Clinics and Practice, 2024 - mdpi.com
Background: Discovering how sex differences impact the efficacy of exercise regimens used
for treating drug addiction is becoming increasingly important. Estrogen is a hormone …
for treating drug addiction is becoming increasingly important. Estrogen is a hormone …